摘要
目的观察护理干预在胆结石合并慢性胃炎患者中的护理效果及对炎症因子的影响。方法选择本院收治的胆结石合并慢性胃炎患者70例,随机分为对照组(n=35)和观察组(n=35)。对照组采用常规方法护理,观察组在对照组基础上采用联合护理干预,采用酶联免疫吸附试验测定两组护理前、后转化生长因子β(TGF-β)、白细胞介素-2(IL-2)及白细胞介素-6(IL-6)水平,比较两组护理效果及对炎症因子的影响。结果观察组护理总满意度(97.14%)显著高于对照组(80.00%),两组比较差异有统计学意义(P<0.05);两组护理前TGF-β、IL-2及IL-6水平比较,差异无统计学意义(P>0.05);观察组护理后TGF-β、IL-2及IL-6水平显著低于对照组(P<0.05);观察组护理后并发症发生率为5.71%,对照组为8.57%,两组护理后并发症发生率比较,差异无统计学意义(P>0.05)。结论胆结石合并慢性胃炎患者治疗过程中在常规护理基础上采用联合护理干预效果理想,能降低炎症因子水平,值得推广应用。
Objective To observe the effect of nursing intervention in the patients with gallstones complicated with chronic gastritis and its effect on inflammatory factors. Methods A total of 70 patients with gallstones complicated with chronic gastritis who were admitted to our hospital were collected. They were randomly divided into the control group（n=35） and the observation group（n=35）. The control group was given conventional nursing methods, and the observation group was given combined nursing intervention on the basis of the control group. The levels of transforming growth factor-β（TGF-β）, interleukin-2（IL-2） and interleukin-6（IL-6） were determined by enzyme-linked immunosorbent assay（ELISA） before and after the nursing in both groups. The nursing effects and the effects on inflammatory factors were compared between the two groups. Results The total nursing satisfaction in the observation group（97.14%） was significantly higher than that in the control group（80.00%）, and there was statistically significant difference between the two groups（P〈0.05）; there was no statistically significant difference in TGF-β, IL-2 and IL-6 levels between the two groups before the nursing（P〉0.05）; the levels of TGF-β, IL-2 and IL-6 in the observation group were lower than those in the control group after the nursing（P〈0.05）; the incidence rate of complications in the observation group was 5.71%, and the incidence rate was 8.57% in the control group. There was no statistically significant difference in the incidence rate of complications between the two groups after the nursing（P〉0.05）. Conclusion The combined nursing intervention on the basis of regular nursing care for the patients with gallstones complicated with chronic gastritis has an ideal effect,which can reduce the level of inflammatory factors and is worthy of promotion and application.
出处
《中国现代医生》
2017年第16期134-137,共4页
China Modern Doctor
基金
浙江省嘉兴市第一批科技计划项目(2016AY23055)
关键词
护理干预
胆结石
慢性胃炎
炎症因子
Nursing intervention
Gallstones
Chronic gastritis
Inflammatory factors
