摘要
目的 分析中药丹参辩证治疗冠心病的机制作用.方法 该实验采用动物进行实际探究,即选取大鼠离体心灌流模型、大鼠心肌缺血模型和家兔室性心动过速模型,随后考察不同组别动物在血流动力学指标、冠脉流量、血清超氧化物歧化酶（SOD）含量、血清丙二醛（MDA）含量的对比结果.结果 给药组经过治疗后SOD含量明显增加,MDA含量则明显降低,2组差异具有统计学意义（P〈0.05）.结论 中药丹参在治疗冠心病上作用显著,有利于患者病情的康复,值得在临床上推广应用.
Objective Analyze the mechanism of traditional Chinese medicine Salvia miltiorrhiza in treating coronary heart disease （CHD）.MethodsThe animal experiment using actual research, namely the selection of rat isolated heart perfusion model, rat model of myocardial ischemia and ventricular tachycardia in rabbits model, then the effects of different animal groups in hemodynamics, coronary flow, serum superoxide dismutase （SOD） content, malondialdehyde （MDA） the results of the content.ResultsAfter treatment, the content of SOD was significantly increased and the content of MDA was significantly decreased in the treatment group, and the difference between the two groups was statistically significant （P〈0.05）.ConclusionTraditional chinese medicine Salvia miltiorrhiza has significant effect on the treatment of coronary heart disease, which is beneficial to the recovery of patients＆#39; condition, and is worthy of clinical application.
作者
厉志莲
李伊佳
张荣坤
LI Zhi-lian LI Yi-jia ZHANG Rong-kun(Jiande First People＇s Hospital of TCM Pharmacy, Hangzhou 311600, China Zhejiang Pharmaceutical College Chinese Medicine Major, Ningbo 315000, China Jiande First People＇s Hospital of Traditional Chinese Medicine, Hangzhou 311600, China)
出处
《中国生化药物杂志》
CAS
2017年第6期89-90,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
中药
丹参
冠心病
活血化瘀
冠脉流量
traditional chinese medicine
salvia miltiorrhiza
coronary heart disease
promoting blood circulation to remove blood stasis
coronary flow
