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基于“方-证要素对应”的甘麦大枣汤治疗脏躁机制分析 被引量:24

Mechanism of Ganmai Dazao Tang in treatment hysteria based on principle of correspondence between formula-syndrome factors
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摘要 甘麦大枣汤是《金匮要略》治疗脏躁的著名方剂。通过总结历代医家相关认识,探讨脏躁的内涵。认为其病机为五脏功能失调,不能潜敛所藏之神,致脏神浮越、心神不安。根据"方-证要素对应"的组方原理,进一步解析甘麦大枣汤的组方用药规律及脏躁的病机特点,并根据现代药理学研究及临床研究进展,分析本方药效物质基础,否定所谓安慰剂效应的观点。甘麦大枣汤组方严谨,构思巧妙,与群方之冠之桂枝汤有相似之处,两方均立足于调和阴阳,故皆在临床应用范围广泛,且效如桴鼓。 Ganmai Dazao Tang is a famous formula for hysteria in Jinguiyaolue( Synopsis of the Golden Chamber). The connotation of hysteria has been explored in the paper through summing up relative knowledge of medical practitioners in the successive dynasties. The pathogenesis of hysteria lies in function disorder of five viscera resulting in that five viscera fail to restrain their spirits,viscera spirits float and heart spirit is uneasy. Hysteria reflects the clinical pathological features of estrangement among qi,blood,yin and yang,and viscera spirits failing to be restrained and floating in the exterior. The combining and medicating laws of Ganmai Dazao Tang,and pathological features hysteria have been further analyzed according to principle of correspondence between formula-syndrome factors. The pharmacodynamic material basis of Ganmai Dazao Tang has been analyzed and the opinion of placebo efficacy has been negated according to the progresses in modern pharmacological research and clinical research. The combination of Ganmai Dazao Tang is rigorous,and similar to Guizhi Tang,the first one of all TCM formulas. These two formulas both are based on regulating yin and yang and widely applied in the clinic with significant curative effects.
作者 王敏 李宇航
出处 《北京中医药大学学报》 CAS CSCD 北大核心 2017年第5期366-370,共5页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家自然科学基金项目(No.81673868) 北京中医药大学"经方现代应用关键科学问题的基础研究"创新团队(No.2011-CXTD-04)~~
关键词 甘麦大枣汤 脏躁 方-证要素对应 Ganmai Dazao Tang hysteria correspondence between formula and syndrome factors
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