摘要
目的:探讨浙江省肿瘤登记地区2010年至2014年癌症死亡的流行病学特征,为制定肿瘤防治计划提供参考依据。方法:数据来源于浙江省14个登记地区上报的2010年至2014年癌症死亡资料,经过分类、审核后计算粗死亡率、标化死亡率、年龄别死亡率、前10位癌症死亡顺位和构成、各年龄段癌症死亡顺位和构成、年度变化百分比(annual percentage change,APC)及其95%可信区间(95%CI)等。结果:2010年至2014年浙江省登记地区共报告癌症死亡病例为108 514例,其中男性70 578例,女性37 936例。恶性肿瘤粗死亡率为186.06/10万,中标率为103.02/10万,世标率为101.73/10万,0~74岁累积死亡率为11.46%。男女性中标死亡率比为1.95,城市与农村比为0.93。年龄40岁以后死亡率上升幅度显著,在年龄≥85岁年龄组达到高峰。癌症粗死亡率从2010年的182.85/10万上升到2014年的191.00/10万,上升了4.46%,经年龄标化之后,中标死亡率则出现下降趋势,由107.85/10万下降至100.60/10万(APC=-1.96%,P=0.017)。肺癌、肝癌和胃癌排在癌症死亡的前3位,前10位癌症合计占全部癌症死亡构成的89.51%,不同年龄段癌症死亡谱不一致,0~14岁儿童白血病死亡率最高,青年组肝癌最高,中老年组肺癌最高。肝癌、胃癌和食管癌死亡率下降,胰腺癌、前列腺癌和卵巢癌死亡率呈现上升趋势。结论:浙江省登记地区癌症粗死亡率呈上升趋势,表明癌症死亡人数将继续增加,中标死亡率下降表明浙江省癌症防控取得一定效果,仍需采用综合性的癌症预防策略,加强癌症的健康教育,推广早诊早治工作,增强癌症的规范化治疗和康复工作,提高生存质量,降低癌症危害。
Objective：To investigate cancer mortality in Zhejiang cancer registration areas from 2010 to 2014. Methods：Cancer regis-tration data were collected from 14 cancer registries of Zhejiang province. The number of cases, crude rates, proportions, age stan-dardized rates, cumulative rates, cut rates, age-specific rates, top 10 mortality ranks, and annual percentage change （APC） of cancer mortality were calculated. Results：A total of 108,514 cancer deaths in Zhejiang cancer registration areas from 2010 to 2014, including 70,578 males and 37,936 females, were recorded. The crude mortality rate was 186.06/105. The standardized mortality rates in Chinese （ASMRC） and world populations were 103.02/105 and 101.73/105, respectively. The cumulative mortality rate （0-74 years old） was 11.46%. The ratio of ASMRC in male and female was 1.95, and that in urban and rural areas was 0.93. Age-specific cancer mortality increased significantly after 40 years old and peaked at the 85＋age group. The crude cancer mortality increased from 2010 （182.85/105） to 2014 （191.00/10^5） by 4.46%. After age standardization, the mortality rate standardized by Chinese population was reduced from 107.85/105 to 100.60/10^5. The APC of ASMRC was-1.96%（P=0.017）. The top three mortality cancers were lung cancer, liver cancer and gastric cancer. The top 10 cancers accounted for 89.51%of all cancer deaths. The mortality rates in different age groups were inconsis-tent. Leukemia was the main cancer type among 0-14-year-old population. Liver cancer was the most common cancer type in 15-44-year-old population. Lung cancer was the main cancer in population above 45 years old. The ASMRCs of liver cancer, gastric cancer and esophageal cancer decreased, whereas those of pancreatic cancer, prostate cancer and ovarian cancer increased. Conclusion：Cancer mortality in Zhejiang cancer registration areas increased, which revealed that the number of cancer deaths will continue to increase. However, the ASMRC decreased, which indicated tha
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2017年第11期552-557,共6页
Chinese Journal of Clinical Oncology
关键词
肿瘤登记
死亡率
死亡顺位
趋势
浙江
cancer registry
mortality
death rank
trend
Zhejiang
