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探讨左旋氨氯地平和氨氯地平治疗高血压的疗效对比

Compare the Efficacy of Amlodipine and Amlodipine in the Treatment of Hypertension
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摘要 目的研究分析高血压患者接受左旋氨氯地平、氨氯地平治疗的临床效果。方法我院对115例高血压患者进行了研究分析,将患者分组为对照组和观察组,对照组57例患者接受苯磺酸氨氯地平片治疗,观察组58例患者接受苯磺酸左旋氨氯地平片治疗,比较分析两组患者的高血压变化、治疗效果、不良反应等指标。结果治疗前后,观察组和对照组患者的SBP和DBP不存在统计学差异性(t=0.378,P=0.706;t=0.187,P=0.352);观察组临床治疗有效率是84.5%,对照组临床治疗有效率是80.7%,两组的临床治疗有效率对比,不具有统计学差异性(χ~2=0.286,P=0.593);观察组患者的不良反应发生率是5.2%,对照组的不良反应发生率是21.1%(χ~2=6.392,P=0.012)。结论高血压患者临床使用左旋氨氯地平、氨氯地平治疗的效果显示,前者的效果优于后者,且临床不良反应发生率比较低,效果比较好。 Objective To study the clinical effects of amlodipine and amlodipine in patients with hypertension. Methods In our hospital were analyzed in 115 cases of patients with hypertension, patients were divided into control group and observation group, the control group of 57 patients received amlodipine besylate tablets treatment, the observation group of 58 patients received levamlodipine besylate tablets treatment, comparative analysis of two groups of patients with high blood pressure, treatment effect, adverse reactions and other indicators. Results Before and after treatment, there was no statistical difference in SBP and DBP between the observation group and the control group (t=0.378, P=0.706, t=0.187, P=0.352); The effective rate of clinical treatment in observation group was 84.5%, and the effective rate of clinical treatment in control group was 80.7%, The effective rate of clinical treatment between the two groups was no statistically significant (χ^2=0.286, P=0.593); The incidence of adverse reactions was 5.2% in the observation group and 21.1% in the control group (χ^2=6.392, P=0.012). Conclusion The effect of amlodipine and amlodipine in the treatment of hypertension patients shows that the former is better than the latter, and thc incidence of adverse reactions is low, and the effect is better.
作者 段文杰
出处 《中国继续医学教育》 2017年第12期202-203,共2页 China Continuing Medical Education
关键词 高血压 左旋氨氯地平 氨氯地平 hypertension levo amlodipine amlodipine
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