摘要
目的:观察温针灸治疗对胚胎移植患者子宫内膜容受性的影响及胚胎移植成功率的临床疗效。方法:将60例胚胎移植患者随机分为温针灸组及对照组,每组各30例。温针灸组,每月于月经前10天开始治疗,治疗至下次月经前一天,月经期不做治疗,此为1疗程,共治疗三个疗程。选穴中脘、天枢、带脉、气海、中极、子宫、血海、足三里、三阴交、太冲,并选双子宫、关元、双足三里穴给予温针灸治疗,均用补法,留针30分钟,治疗3个月经周期后开始胚胎移植。对照组选取相应的穴位,于月经前10天开始给予压豆治疗,患者仅仅有轻微的表皮刺激,没有"得气"感,留针至30min,并给予电磁波烤电灯产生热的感觉,不用艾灸治疗,不起任何治疗作用,观察3个月经周期后开始胚胎移植。观察并比较两组患者的治疗前后的临床妊娠率、子宫内膜水平的变化分型、子宫动脉搏动指数(PI)、子宫动脉血流阻力指数(RI)。结果:(1)临床妊娠率:温针灸组30例中,14例受孕,临床妊娠率为46.67%(14/30),对照组30例中,7例受孕,临床妊娠率为23.33%(7/30,P<0.05)。(2)温针灸组在改善子宫内膜分型方面具有较好的疗效,温针灸组在治疗后子宫内膜分型中A型比例增加,与对照组比较(15VS10),差异有统计学意义(P<0.05)。(3)温针灸组治疗3个月经周期后,排卵后第七日子宫内膜血流参数PI(0.751±0.012VS0.870±0.020),RI(0.530±0.021VS0.552±0.010)均低于对照组,差异具有统计学意义(P<0.05),对照组治疗后的子宫内膜血流参数变化不明显(P>0.05)。结论:温针灸可提高胚胎移植临床妊娠成功率,并且在改善患者内膜水平、子宫动脉搏动指数(PI)、子宫动脉血流阻力指数(RI)有显著优势,可能的机制为对患者子宫内膜容受性有良好的影响。
Objective ： To observe the temperature acupuncture treatment and the receptivity of endometrium in patients with embryo transfer and the influence of the clinical curative effect of embryo transfer success rate. Methods ： 60 patients with embryo transfer were randomly divided into acupuncture group and controlled group, 30 cases in each group. Warming acupuncture group, every month 10 days prior to the period starting treatment, the treatment to the day before the next time menstruation, menstrual period do not treatment, this was a course of treatment, a total of three courses of treatment. Choosing acupuncture point often, day pivot, brought a pulse, sea, air, extremely, the uterus, blood, foot three mile, three vaginal intercourse, lr 3, and chooseing double uterus, Guanyuan, double foot three mile point to give warming acupuncture treatment, filling method, 30 rain, retaining needle treatment of three menstrual cycles after embryo transfer. The controlled group selected the corresponding acupuncture points in just 10 days before menstruation to give pressure treatment, patients with only mild skin stimulation, no sense of ＂ Qi＂ , retaining needle to 30 min, and give the electromagnetic wave roast lamp produces hot feeling, don＇t use moxi- bustion treatment, no treatment, began to observe after embryo transfer three menstrual cycles. To observe and compare the two groups before and after treatment in patients with theclinical pregnancy rate, the level of endometrial changes in classification, u- terine artery pulsation index （ PI）, uterine artery blood flow resistance index （RI）. Results ： （ 1 ） The clinical pregnancy rate ： 30 cases in the warming acupuncture group, 14 cases of pregnancy, the clinical pregnancy rate was 46. 67% （14/30）, 30 cases in the controlled group, 7 cases of pregnancy, the clinical pregnancy rate was 23. 33% （7/30, P 〈 0. 05）. （2） Warming ac- upuncture group in improving the endometrial parting ways had good curative effect, warming acupuncture gr
出处
《四川中医》
2017年第6期184-187,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
新疆医科大学第一附属医院院内课题资助项目(编号:2014ZRQN19)
关键词
温针灸
胚胎移植
子宫内膜容受性
疗效观察
Warming acupuncture
Embryo transfer
Receptivity of endometrium
Clinical observation
