摘要
目的了解我国视神经脊髓炎谱系疾病患者的临床特点。方法检索维普数据库1989年至2016年收录的视神经脊髓炎谱系疾病病例报道文献,并分析所报道病例的临床特点。结果共纳入87个相关研究,共计109例患者,男女比例为1∶4,发病年龄为576(38.44±17.08)岁,诱因多为受凉感冒(12.80%),66.05%以视神经炎症状为首发症状,23.85%以脊髓炎为首发症状。脊髓磁共振显示累及到胸髓者80.73%,颈髓占49.54%,腰椎占10.09%,12.84%累及最后区。结论视神经脊髓炎谱系疾病好发于青壮年,女性多见,男女发病年龄无明显差异,首发症状以视神经炎多见,脊髓病灶以胸髓多见。
Objective To investigate the clinical features of patients with neuro- myelitisoptica spectrum disorders （ NMOSD ） in China. Methods Cases reports of NMOSD from 1989 to 2016 were retrieved from the database of Weipu data basis, and the clinical features of cases reported were analyzed. Results Eighty-seven studies were enrolled. Totally 109 patients were included. The ratio of male to female was 1 ： 4 and the mean onset age was （38.44 ± 17.08 ） years （range 5 -76 years）. The predispo- sing factors was catching a cold（ 12.80% ）. There were 66.05% patients with optic neu- ritis symptoms as initial symptoms, 23.85% with spinal cord inflammation as the first symptom. Spinal magnetic resonance showed that 80.73% of the lesions involved tho- racic spinal cord, and the cervical spinal cord occupied by 49.54% , while the lumbar spine accounted for about 10.09%. 12.84% involved the final area. Conclusion In China, NMSOD is common in young adults, and more common in women. The onset age between the male and female has no significant difference. The first symptom of optic neuritis is more common, and the spinal cord lesion in thoracic cord is popular.
出处
《眼科新进展》
CAS
北大核心
2017年第6期548-550,共3页
Recent Advances in Ophthalmology
基金
国家自然科学基金资助(编号:81460088)
江西省高等学校科技落地计划项目(编号:KJLD14017)
南昌大学研究生创新专项资金项目(编号:cx2016335)~~
关键词
视神经脊髓炎谱系疾病
视神经炎
临床特点
vneuromyelitisoptica spectrum disorders
optic neuritis
clinical feature
