摘要
目的建立测定银朱中可溶性汞的方法。方法使用双硫腙分光光度法分析银朱在不同溶出介质、不同溶出转速、不同溶出时间下可溶性汞的含量。结果选出溶出量最大的溶出介质为人工胃液,转速150 r·min^(-1),时间2 h,并建立相应的检测方法。结论银朱汞的溶出量极少,具有安全性。
OBJECTIVE To establish the quantification method of soluble mercury salts from Vermilion. METHODS Determina- tion of the quantity of soluble mercury salts from Vermilion in different dissolution solution, dissolution speed and dissolution duration was carried out using the dithizone spectrophotometric determination. RESULTS The optimal dissolution condition of Vermilion was chosen, which was dissolved in artificial gastric fluid for 2 h with dissolution speed of 150 r· min- 1, and the quantification method was established. CONCLUSION The quantity of soluble mercury salts from Vermilion is little,and Vermilion is proved safe.
出处
《华西药学杂志》
CAS
CSCD
2017年第3期312-314,共3页
West China Journal of Pharmaceutical Sciences
关键词
银朱
可溶性汞
双硫腙
乙二胺四乙酸二钠
分光光度法
硫化汞
人工胃液
朱砂
Vermilion
Soluble mercury salts
Dithizone
EDTA
Spectropbotometric determination
HgS
Artificial gastric fluid
Cinnabar
