摘要
目的探讨新型矿化胶原应用于四肢骨缺损的疗效。方法回顾性分析2013年1～12月收治的35例四肢骨缺损患者临床资料，手术治疗采用新型矿化胶原作为骨缺损区填充材料，术后定期随访，采用Lane—SandhuX线评分标准评估骨缺损愈合情况。结果随访时间12个月，其中3例患者伤口出现红肿，经换药后2例甲级愈合，1例乙级愈合。术后1个月Lane—SandhuX线评分：20例患者评分3分，15例患者评分2分；术后6个月Lane—SandhuX线评分：21例患者评分9分，10例评分8分，4例评分7分；术后12个月Lane．SandhuX线评分：28例评分12分，7例评分11分。术后6个月评分与术后1个月评分差异有统计学意义[（2．60±0．49）分比（8．49±0．12）分，t=107．860，P=0．000）]；术后12个月评分与术后6个月评分差异有统计学意义[（8．49±0．12）分比（11．8±0．06）分，t=41．630，P：0．000）]。结论新型矿化胶原安全有效，可作为骨缺损填充材料，临床效果良好。
Objective To discuss the outcome of repair of limbs bone defect by using mineralized collagen graft. Methods The clinical data of 35 cases who diagnosed the existence of bone defect from January 2013 to December 2013 in our department were retrospectively analyzed. After operation, Lane Sandhu X -ray score standard was evaluated. Results All patients were ibllowed up for 12 months. Postoperative 1 month, Lane Sandhu X - ray score was 3 points in 20 cases and 15 cases with 2 pointss;postoperative 6 months, Lane Sandhu X -ray score was 9 points in 21 cases, 10 cases with 8 points and 4 cases with 7 points. Postoperative 12 months, Lane Sandhu X- ray score was 12 points in 28 cases,7 cases with 11 points. The scores of postoperative 6 months were better than the scores of postoperative 1 month [ （2.60 ±0.49） points vs. （8.49 ±0.12） points,t = 107. 860,P =0.000]. There was significant difference between the scores of postoperative 12 months and scores of postoperative 6 months [ （8.49 ± 0. 12） points vs. （ 11.8 ± 0.06） points, t = 41. 630,P = 0. 000 ]. Conclusion MC is used as an effective bone substi- tute material, and its clinical effect is good.
作者
高冲
高健
田伟
侯建文
王玺
贾学军
寇剑铭
Gao Chong Gao Jian Tian Wei Hou Jianwen Wang Xi Jia Xuejan Kou Jianming(Department of Orthopedics, the Second People＇s Hospital of Lianyungang, Lianyungang, Jiangsu 222000, Chin Department of Orthopedics ,the Sixth Affiliated Hospital of Xinfiang Medi- cal University, Urumqi ,Xinjiang 830002, China)
出处
《中国基层医药》
CAS
2017年第12期1775-1778,I0002,共5页
Chinese Journal of Primary Medicine and Pharmacy
基金
江苏省卫生计生委科研项目（H201559）
关键词
骨代用品
骨疾病
创伤和损伤
Bone Substitutes
Bone disease
Wounds and injuries
