摘要
目的探究分析派特灵宫颈治疗对宫颈高危型人乳头瘤病毒（human papiloma virus,HPV）感染转归的影响。方法随机选取浙江省象山县第一人民医院在2014年1月~2016年1月期间收治的120例宫颈高危型HPV感染患者为研究对象,其中40例患者采用派特灵治疗（派特灵组）,40例患者采用膦甲酸钠治疗（膦甲酸钠组）。另外40例患者不作干预（对照组）。对比观察3组患者HPV感染的转归情况。结果特派灵组患者转阴率（87.50%）与膦甲酸钠组（55.00%）和对照组（50.00%）比较具有统计学意义（P〈0.05）,且特派灵组患者的持续阳性率（2.50%）明显低于对照组（42.50%）和膦甲酸钠组（37.50%）。但是各组之间的好转率和新发感染率比较差异不显著。对照组转阴率（50.00%）和持续阳性率（42.50%）与膦甲酸钠组的比较均无显著差异。结论派特灵治疗宫颈高危型HPV感染的临床效果显著,能够有效改善HPV感染症状,能够缩短HPV转阴时间,具有积极的临床意义。
Objective To explore the treatment effect on cervical Paiteling cervical high-risk human papiloma virus（HPV） infection outcome.MethodsRandomly selected from our hospital during January 2014 to January 2016 in 120 cases of cervical high-risk HPV infection patients as the research object, of which 40 cases were treated with Paiteling treatment （Paiteling group）, 40 patients were treated with foscarnet sodium （foscarnet sodium group）.Another 40 patients without intervention （control group）.The outcome of HPV infection in three groups was compared.ResultsPatients with negative rate of special spirit （87.50%） and foscarnet sodium group （55.00%） and control group （50.00%） was statistically significant（P〈0.05）, and the special spirit Group continued the positive rate （2.50%） was significantly lower than the control group （42.50%） and foscarnet sodium group （37.50%）.However, there was no significant difference between the groups in the rate of improvement and the incidence of new infections.There was no significant difference between the control group and the positive rate （50.00%） in the control group （42.50%） compared with that in the control group.ConclusionPaiteling treatment of clinical effect of cervical high-risk HPV infection, can effectively improve the symptoms of HPV infection, which can shorten the HPV clearance time, has positive clinical significance.
出处
《中国生化药物杂志》
CAS
2017年第5期122-124,共3页
Chinese Journal of Biochemical Pharmaceutics
