摘要
目的:探讨三重抗血小板治疗预防支架辅助弹簧圈栓塞术后缺血性事件的有效性。方法:拟行支架辅助弹簧圈栓塞术的颅内动脉瘤患者96例,纳入双重和三重治疗组,各48例;术前分别接受双重和三重抗血小板治疗。记录术后5个月缺血性、出血性事件的发生率及其他不良反应。结果:双重治疗组缺血性事件发生率显著高于三重治疗组(P=0.04);2组出血性事件发生率差异无统计学意义(P=0.31)。结论:三重抗血小板治疗比双重抗血小板治疗能更有效地预防支架辅助弹簧圈栓塞术后缺血性事件的发生。
Objective： To investigate the clinical efficacy of triple antiplatelet therapy to prevent the ischemic incidence after stent-assisted coil embolization. Methods： Ninety-six patients with intracranial aneurysm who underwent the stent-assisted coil embolization were enrolled and randomly divided into dual antiplatelet therapy group and triple antiplatelet therapy group with 48 cases in each group. The patients in the both groups received preoperative dual or triple stent-assisted coil embolization, respectively. The incidence of ischemic and bleeding events and the adverse effects during 5 months after the operation were recorded. Results： The incidence rate of ischemic events in the dual antiplatelet therapy group was significantly higher than that in the triple antiplatelet therapy group （P=0.04）. The difference of bleeding events between the 2 groups was not statistically significant （P=0.31）. Conclusion： Compared with dual antiplatelet therapy, the triple antiplatelet therapy can prevent the occurrence of the ischemic events after stent-assisted coil embolization more efficiently.
出处
《神经损伤与功能重建》
2017年第3期209-211,共3页
Neural Injury and Functional Reconstruction
