摘要
恶性肿瘤严重威胁人类的健康,随着老龄化进程的加快、生活方式的改变以及环境的恶化,恶性肿瘤的发病率和病死率也逐年增高。手术切除是许多恶性肿瘤的首选治疗方法,但即使将恶性肿瘤完全切除,许多患者仍死于术后癌症的复发或转移。免疫系统与恶性肿瘤的发生、发展、复发以及转移密切相关,围术期许多因素可能会抑制机体免疫功能,增加恶性肿瘤复发及转移的风险,因此研究影响恶性肿瘤手术患者围术期免疫功能的因素,对于延长患者生存时间、改善生存质量具有重要的意义。
Malignant tumor is a serious threat to human health. As the acceleration of the aging process, as well as changes in lifestyle and the deterioration of the environment, the incidence and mortality of malignant tumors have been increasing year by year. Surgical resection is usually the first choice of treatment of localized malignant tumors. However, many patients die of recurrence or metastasis even after complete resection. The immune system is closely related to the occurrence, development, recurrence and metastasis of malignant tumors. Many perioperative factors may inhibit the immune function and increase the risk of recurrence and metastasis. Therefore, it is of great significance to study the factors that affect the perioperative immune function of patients with malignant tumor,which can prolong the survival time and improve the quality of life.
出处
《医学综述》
2017年第11期2176-2180,共5页
Medical Recapitulate
基金
国家自然科学基金(81570044)
山东省自然科学基金(ZR2015HM038)
深圳市科技计划项目(JCYJ20150402105524051)
关键词
肿瘤
围术期免疫功能
手术
低体温
麻醉
输血
Tumor
Perioperative immune function
Surgery
Hypothermia
Anesthesiology
Transfusion
