摘要
目的研究对比原发性高血压患者的两种主要中医体质与其发生发展的内在关系。方法采取整群抽样法选取900例阴虚质原发性高血压患者作为阴虚组、900例痰湿质原发性高血压患者作为痰湿组,采集两组患者的基本信息、个人健康信息,对比两组患者的体格检查、实验室检查、靶器官损害辅助检查指标的水平。结果痰湿组患者的体质量指数、腹围高于阴虚组,差异具有统计学意义(t=26.399、19.849,P<0.05);两组患者的身高、收缩压、舒张压比较,差异均无统计学意义(t=0.694、0.820、1.336,P>0.05)。痰湿组患者的甘油三酯、空腹血糖、血尿酸均高于阴虚组,差异具有统计学意义(t=40.342、24.991、20.895,P<0.05)。痰湿组患者的24 h尿蛋白低于阴虚组,颈动脉内中膜厚度高于阴虚组,左室射血分数低于阴虚组,差异具有统计学意义(t=22.027、23.387、19.844,P<0.05)。结论阴虚质、痰湿质原发性高血压患者的临床特点各不相同,临床上治疗原发性高血压患者可根据其中医体质辨证分型实施有针对性的治疗,以提高原发性高血压患者的血压控制效果。
Objective To study and compare the internal relation of occurrence and development of two main constitutions of traditional Chinese medicine in primary hypertension patients. Methods A total of 900 Yin deficiency of primary hypertension as Yin deficiency group and 900 phlegm-dampness of primary hypertension as phlegm-dampness group. Collection were made on basic information and personal health information in two groups, and comparison were made on physical examination, laboratory examination and target organ damage of auxiliary examination index levels in two groups. Results The phlegm-dampness group had higher body mass index and abdominal girth than Yin deficiency group, and the difference had statistical significance （t=26.399, 19.849, P〈0.05）. Both groups had no statistically significant difference in height, systolic blood pressure and diastolic blood pressure （t=0.694, 0.820, 1.336, P〉0.05）. The phlegm-dampness group had higher triglycerides, fasting blood glucose and blood uric acid than Yin deficiency group, and the difference had statistical significance （t=40.342, 24.991, 20.895, P〈0.05）. The phlegm-dampness group had lower 24 h urine protein than Yin deficiency group, higher carotid intima-media thickness than Yin deficiency group, and lower left ventricular ejection fraction than Yin deficiency group. Their difference had statistical significance （t=22.027, 23.387, 19.844, P〈0.05）. Conclusion Yin deficiency and phlegm-dampness of primary hypertension patients have different clinical characteristics, and constitution of TCM syndrome differentiation should be based on to implement targeted therapy, so as to improve the effect of blood pressure control of patients with primary hypertension.
出处
《中国实用医药》
2017年第13期19-21,共3页
China Practical Medicine
基金
深圳市宝安区科技局(项目编号:2015180)
关键词
原发性高血压
中医体质
阴虚质
痰湿质
Primary hypertension
Constitutions of traditional Chinese medicine
Yin deficiency constitution
Phlegm-dampness constitution
