摘要
目的分析2010-2014年新报告现住址为伊宁市的艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)的失访情况及其可能的影响因素,为HIV/AIDS病人管理提供依据。方法通过艾滋病综合防治数据信息管理系统,收集2010-2014年新报告伊宁市HIV/AIDS病人的相关信息,对HIV/AIDS病人的一般情况和失访情况进行描述,应用COX比例风险回归模型分析其失访率影响因素。结果 2010-2014年新报告伊宁市HIV/AIDS病人共有2 534例,累计随访观察6 634.59人年,失访284人,失访率0.042 8/人年。失访的284例HIV/AIDS病人中,男性占66.90%,失访率为0.055 1/人年,女性占33.10%,失访率为0.029 5/人年;HIV感染者占89.79%,失访率为0.049 5/人年,AIDS病人占10.21%,失访率为0.019 5/人年;本县市报告者占83.80%,失访率为0.037 6/人年;未参加抗病毒治疗人群占失访人群的82.04%,失访率为0.054 9/人年。COX比例风险模型回归多因素分析结果显示,与报告单位为本县市相比,本州外县市[风险比(HR)=2.06,95%可信区间(CI):1.12~3.78]、本省外县市(HR=2.23,95%CI:1.40~3.52)和外省市报告(HR=2.13,95%CI:1.26~6.61)都会增加失访风险。未接受抗病毒治疗HIV/AIDS病人的失访率是参加抗病毒治疗的18.70倍(HR=18.70,95%CI:13.76~25.40)。结论加强流动性HIV/AIDS病人的随访管理,优化高危人群干预模式,降低失访率。
Objective To analyze the lost to follow-up rate of the newly reported HIV/AIDS cases in Yining city during 2010-2014 and its influence factors, and to provide the basis for the future management of people living with HIV/AIDS. Methods Data were collected from the information management system of HIV/AIDS prevention and control during 2010-2014 to know the newly reported HIV/AIDS cases in Yining, including their demographic characteristics, infectious status, the disease stage and antiviral treatment status, sample sources, and the condition of case follow-up, etc. Cox proportional hazards regression model was used to analyze the lost to follow-up rate and influence factors. Results There were newly reported 2534 HIV/AIDS cases during 2010-2014, and the cumulative follow-up observation of 6 634.59 person year. 284 people were lost to follow-up, with the rate of 0. 042 8 person year, and 66.90% of men （0. 0551 person year） and 33.10% of women （0. 0295 person year） ; HIV cases accounted for 89.79%, with 0. 0495 person year, and AIDS for 10.21% with 0. 0195 person year lost to follow-up. 83.80% of them were local people with 0. 0376 person year lost to follow-up; 82.04% did not receive antiviral treatment with 0. 0549 person year lost to follow-up. Cox proportional hazards regression model showed that non-local people living with HIV/AIDS and those without receiving antiviral treatment had higher risks of loss to follow-up and the latter was 18.70 times more than those receiving ART to be lost to follow up （HR= 18.70, 95% CI： 13.76-25.40） . Conclusion It is necessary to strengthen the follow up visits to the people living with HIV/AIDS, esp. the migrant HIV/AIDS people, to optimize the high-risk behavior intervention, and to reduce the rate of lost to follow-up.
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2017年第5期414-417,共4页
Chinese Journal of Aids & STD
