摘要
目的系统评价体位变换对结肠息肉及腺瘤检出率的影响,为临床结肠镜检查提供指导。方法检索Embase、Pub Med、The Cochrane library和CBM数据库(检索时间均从建库至2016年10月),根据纳入和排除标准筛选文献,按Cochrane系统评价方法评价纳入研究的质量,并进行描述性分析。结果共纳入6篇文献,包括3篇随机平行对照试验及3篇随机交叉试验。结果显示,4篇研究表明结肠镜检查退镜过程中体位变换可提高息肉检出率,其中3篇研究提示体位变换可进一步提高腺瘤检出率。2篇随机平行对照试验表明体位变换并不能显著提高腺瘤检出率。结论现有证据表明,在结肠镜检查退镜过程中采取体位变换对息肉及腺瘤检出率的影响尚无定论。因此,在今后更多的高质量研究证明之前,体位变换尚不能常规应用于结肠镜检查。
Objective To systematically review the impact of position change on the rate of colon polyps and adeno- mas, providing guidance for clinical colonoscopy. Methods We electronically searched Embase, PubMed, The Cochrane li- brary and CBM database (databases up to October 2016 ), according to inclusion and exculsion criteria; the quality of the in- cluded studies was evaluated according to the Cochrane systematic evaluation method and descriptive analysis was performed. Results A total of 6 articles were included, consisting of 3 random parallel controlled trials and 3 random crossover trials. 4 studies showed that position change improves polyp detection and 3 of them showed that position change also improves adenoma detection rate. 2 random parallel controlled trials suggested that position change did not significantly improve adenoma detection rate. Conclusion Existing evidence suggests that the impact of position change on polyp and adenoma detection rate is uncer- tain. Therefore, position change can not be used routinely in colonoscopy before more high quality researches prove this observa- tion.
出处
《临床合理用药杂志》
2017年第14期13-16,18,共5页
Chinese Journal of Clinical Rational Drug Use
关键词
体位变换
结肠镜
息肉检出率
腺瘤检出率
Position change
Colonoscopy
Adenoma detection rate
Polyp detection rate