摘要
目的分析肝硬化患者并发肝性脑病的相关危险因素及预后。方法选取我院2013年1月至2015年12月收治的83例单纯肝硬化患者作为对照组,选取同期76例肝硬化并发肝性脑病患者作为研究组,收集可能导致肝性脑病的临床资料,分析肝硬化患者并发肝性脑病的危险因素及预后。结果研究组的血氨(AM)、血糖、谷丙转氨酶(ALT)、血清总胆红素(TBIL)、血尿素氮(BUN)、血肌酐(SCr)和凝血酶原时间(PT)水平均高于对照组(P<0.05)。研究组的感染、上消化道出血和腹水发生率均高于照组(P<0.05),而血钠(Na+)和血清白蛋白(ALB)水平均低于照组(P<0.05)。研究组预后良好率为63.16%,低于对照组的83.13%(P<0.05)。结论针对肝性脑病发生的危险因素对患者进行提前干预,可预防肝性脑病,改善预后。
Objective To analyze the relative risk factors and prognosis of hepatic encephalopathy in patients with liver cirrhosis. Methods 83 cases of patients with liver cirrhosis admitted to our hospital from January 2013 to December 2015 were selected as control group, and 76 cases of patients with liver cirrhosis and hepatic encephalopathy in the same period were selected as study group. Patients＇ clinical datas that possibly lead to hepatic encephalopathy were collected. The risk factors and prognosis of hepatic encephalopathy in patients with liver cirrhosis were analyzed. Results The blood ammonia （AM）, blood glucose, alanine aminotransferase （ALT）, serum total bilirubin （TBIL）, blood urea nitrogen （BUN）, serum creatinine （SCr） and prothrombin time （PT） levels of study group were higher than those of control group （all P〈0.05）. The incidences of infection, upper gastrointestinal bleeding and ascites of study group were higher than those of control group （all P〈0.05）, but the serum sodium （Na＋） and serum albumin （ALB） levels were lower than those of control group （both P 〈0.05）. The prognostic good rate of study group was 63.16%, lower than 83.13 % of control group （P 〈0.05）. Conclusions Patients receiving advanced intervention according to risk factors of hepatic encephalopathy can prevent hepatic encephalopathy and improve prognosis.
出处
《临床医学工程》
2017年第5期649-650,共2页
Clinical Medicine & Engineering
关键词
肝硬化
肝性脑病
危险因素
预后
Liver cirrhosis
Hepatic encephalopathy
Risk factors
Prognosis
