摘要
目的探讨经子宫动脉途径介入治疗子宫切口妊娠的疗效。方法选取我院2013年12月~2015年12月诊治的子宫切口妊娠患者134例,采用随机数字表法分为两组,对照组患者67例实施甲氨蝶呤病灶介入治疗术,观察组患者67例实施子宫动脉介入栓塞术+清宫术,比较两组患者治疗前后临床指标、治疗效果、并发症情况。结果与治疗前比较,治疗后两组患者血β-人绒毛膜促性腺激素(β-HCG)、孕酮水平均有所降低,且观察组患者血β-HCG[(143.7±21.5)U/L]、孕酮[(5.8±0.6)nmol/L]水平低于对照组[(271.9±34.8)U/L、(7.1±1.0)nmol/L];观察组患者术中出血量[(68.5±7.1)ml]、住院费用[(14 502.6±1137.9)元]均少于对照组[(189.2±10.3)ml、(16 387.2±1305.4)元];住院时间[(11.7±1.6)d]、血β-HCG恢复正常时间[(10.7±1.2)d]、孕酮恢复正常时间[(5.7±1.3)d]、月经恢复正常时间[(52.6±4.3)d]均短于对照组[(15.3±2.1)、(13.6±1.4)、(7.9±1.1)、(70.8±5.9)d];并发症发生率(3.0%)低于对照组(11.9%);差异均有统计学意义(P<0.05)。结论经子宫动脉途径介入治疗子宫切口妊娠的效果显著,具有创伤小、术后恢复快、经济、安全等优点,值得临床推广使用。
Objective To explore the efficacy of uterine artery interventional treatment in uterine incision pregnancy.Methods 134 patients with uterine incision pregnancy in our hospital from December 2013 to December 2015 were selected and divided into two groups according to random number table method with 67 cases in each group.Patients in the control group received methotrexate lesion intervention.Patients in the observation group received uterine artery intervention ＋curettage.The clinical indexes before and after treatment,treatment effect and complications were compared between two groups.Results After treatment,the levels of serum β-HCG and progesterone of patients in two groups were decreased,and those in the observation group [（143.7 ±21.5）U/L,（5.8±0.6）nmol/L] were lower than those in the control group [（271.9±34.8）U/L,（7.1±1.0）nmol/L];the amount of bleeding during operation [（68.5 ±7.1）ml] and hospital costs[（14 502.6 ±1137.9） Yuan] in the observation group were less than those in the control group [（189.2 ±10.3）ml,（16387.2 ±1305.4）Yuan].The time of hospitalization,serum β-HCG,progesterone and menstruation returning to normal[（11.7 ±1.6）,10.7 ±1.2）,（5.7 ±1.3）,（52.6 ±4.3）d] in the observation group were shorter than those in the control group[（15.3±2.1）,（13.6±1.4）,（7.9±1.1）,（70.8±5.9）d];the incidence of complications in the observation group（3.0%） was lower than that in the control group（11.9%）,and all the differences were statistically significant（P〈0.05）.Conclusion Uterine artery interventional treatment has significant effect in uterine incision pregnancy,which has the advantages of small wound,fast recovery,economy,safety and so on.It is worthy of clinical application.
出处
《中国当代医药》
2017年第8期96-98,共3页
China Modern Medicine
