摘要
目的观察环磷腺苷葡胺治疗慢性心力衰竭(CHF)的临床效果。方法选取2014年8月—2015年8月在本院住院治疗的60例慢性心力衰竭患者作为研究对象,随机分为两组,每组各有30例,对照组给予常规药物治疗,观察组在对照组治疗的基础上,静脉滴注含120~180mg的环磷腺苷葡胺的250 ml的5%葡萄糖(如为糖尿病患者上述液体中加入4 U普通胰岛素),1次/天,疗程5~7 d,比较两组临床疗效以及心功能改善情况。结果观察组患者在治疗慢性心力衰竭的临床疗效总有效率、左心室射血分数上升的幅度、血浆脑钠肽(BNP)下降的水平优于对照组患者,差异具体统计学意义(P<0.05)。结论常规治疗的基础上加环磷腺苷葡胺治疗慢性心力衰竭的疗效优于常规治疗。
Objective To observe the clinical effect ofmeglumine adenosine monophosphate in the treatment of chronic heart failure （CHF）. Methods From August 2014 to August 2015 in 60 cases of chronic heart failure patients hospitalized in our hospital as the research object, randomly divided into two groups, each group had 30 cases, the control group was given routine drug treatment, the observation group based on the treatment in control group, 5% glucose 250 ml McAMP intravenous injectionwith 120-180 mg the （such as diabetes in the liquid with 4 U insulin）, 1 times / day, 5 to 7 days treatment, compared two groups of clinical curative effect and the improvement of heart function. Results The observation group in the treatment of patients with chronic heart failure clinical curative effect, the total efficiency of left ventricular ejection fraction increased, plasma brain natriuretic peptide （BNP） level is better than the decline of the patients in the control group, the difference was statistically significant specific （P〈0.05）. Conclusion Treatment of chronic heart failure based on routine treatment plus meglumine adenosine monophosphate is better than conventional therapy.
出处
《中国继续医学教育》
2017年第8期178-180,共3页
China Continuing Medical Education
关键词
环磷腺苷葡胺
慢性心力衰竭
临床疗效
meglumine adenosine
chronic heart failure
clinical efficacy
