摘要
目的:观察补肾益气方治疗黄体功能不全所致自然流产的临床疗效,及对患者血清人绒毛膜促性腺激素(β-HCG)、孕酮(P)、雌二醇(E_2)水平的影响。方法:选取在本院接受治疗的120例黄体功能不全所致自然流产患者,随机分为对照组、中药组及中西医结合组,每组40例。对照组不做任何处理,中药组给予补肾益气方治疗,中西医结合组在给予补肾益气方治疗时额外肌肉注射黄体酮。中药组和中西医联合组均连续用药3月。观察3组血清β-HCG、P、E_2水平的变化,比较3组足月分娩率。结果:孕1月,3组血清β-HCG、P及E_2水平比较,差异均无统计学意义(P>0.05)。孕2月,中药组和中西医结合组血清β-HCG、P及E_2水平均高于对照组(P<0.05),中西医结合组3项指标水平均高于中药组(P<0.05)。孕3月,中药组和中西医结合组血清β-HCG、P及E_2水平均高于对照组,中西医结合组3项指标水平均高于中药组(P<0.05)。对照组足月分娩率62.5%(25/40),中药组足月分娩率82.5%(33/40),中西医结合组足月分娩率90.0%(36/40)。中药组和中西医结合组的足月分娩率均高于对照组(P<0.05,P<0.01)。结论:补肾益气方联合黄体酮注射液治疗黄体功能不全所致自然流产,可提高孕妇血清中的β-HCG、P及E_2水平,有较好的保胎效果。
Objective：To observe the clinical effect of Bushen Yiqi prescription combined with progesterone in treating spontaneous abortion caused by luteal phase defect and the effect on levels of β-human chorionic gonadotropin（β-HCG）,progesterone（P） and estrogen（E2） of patients. Methods：Selected 120 patients with spontaneous abortion caused by luteal phase defect who received treatment in our hospital,and divided them into the control group,Chinese medicine group and the combination group randomly,40 cases in each group. The control group received no treatment,Chinese medicine group received Bushen Yiqi prescription for treatment,and the combination group received Bushen Yiqi prescription combined with intramuscular injection of progesterone for treatment. Both Chinese medicine group and the combination group received treatment for 3 months continuously. Observed changes of levels of β-HCG,P and E2,and compared full-term birth rate in three groups. Results：After one month of pregnancy,compared levels of β-HCG,P and E2 in three groups,there was no significant difference（P〉0.05）. After two months of pregnancy,levels of β-HCG,P and E2 in Chinese medicine group and the combination group were all higher than those in the control group（P〈0.05）, and levels of these three indexes in the combination group were higher than those in Chinese medicine group（P〈0.05）. After three months of pregnancy,levels ofβ-HCG,P and E2 in Chinese medicine group and the combination group were all higher than those in the control group（P〈0.05）,and levels of these three indexes in the combination group were higher than those in Chinese medicine group（P〈0.05）.The full-term birth rate was 62.5%（25/40） in the control group,82.5%（33/40） in Chinese medicine group,and 90.0%（36/40）in the combination group. Full-term birth rate in Chinese medicine group and the combination group were higher than that in the control group（P〈0.05,P〈0.01）. Conclusion：The therapy of Bushen Yiqi prescriptio
出处
《新中医》
CAS
2017年第5期85-87,共3页
New Chinese Medicine
