摘要
目的:观察中西医结合治疗急性胆源性胰腺炎的临床疗效。方法:选取84例肝胆湿热型急性胆源性胰腺炎患者作为研究对象,按照随机双盲法将患者分为观察组与对照组各42例。对照组给予常规西药联合内镜介入治疗,观察组在此基础上加用复方大柴胡汤治疗,2组患者均连续治疗15天。观察2组患者治疗前后碱性磷酸酶(ALP)、谷丙转氨酶(ALT)、血淀粉酶及尿淀粉酶的变化情况,评估临床治疗效果,统计并发症发生率。结果:治疗后,观察组与对照组总有效率分别为90.48%、73.81%,2组比较,差异有统计学意义(P<0.05)。2组ALP、ALT、血淀粉酶及尿淀粉酶均较治疗前下降(P<0.05),而观察组各指标值均低于对照组(P<0.05)。治疗过程中,观察组并发症发生率为7.14%,对照组并发症发生率为33.33%,2组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗急性胆源性胰腺炎临床疗效显著,可有效改善患者的临床症状,且并发症少,值得在临床中推广应用。
Objective：To observe the clinical effect of integrated Chinese and western medicine therapy in treating acute biliary pancreatitis. Methods：Eighty-four cases of patients with acute biliary pancreatitis of dampness and heat in liver and gallbladder type were selected as study objects,and were divided into the observation group and the control group randomly by using the random double-blind method,42 cases in each group. Both groups were treated with routine western medicine combined with endoscopic interventional treatment, while the observation group was additionally treated with compound Dachaihu tang. Both groups received treatment for 15 days continuously. Observed changes of alkaline phosphatase（ALP）,alanine transaminase（ALT）,hemodiastase and urine amylase in both groups before and after treatment. Assessed the clinical effect,and recorded the complication rate in both groups. Results：After treatment,the total effective rate was 90.48% in the observation group and 73.81% in the control group,the difference being significant（P〈0.05）. ALP,ALT,hemodiastase and urine amylase in both groups were decreased when compared with those before treatment（P〈0.05）. And all these indexes in the observation group were lower than those in the control group（P〈0.05）. During treatment,the complication rate was7.14% in the observation group and 33.33% in the control group, the difference being significant（P〈0.05）. Conclusion：Integrated Chinese and western medicine therapy for acute biliary pancreatitis has significant curative effect, which can effectively improve clinical symptoms. It has less complication and great clinically applicable value.
出处
《新中医》
CAS
2017年第5期54-56,共3页
New Chinese Medicine
关键词
急性胆源性胰腺炎(ABP)
肝胆湿热证
中西医结合疗法
大柴胡汤
内镜介入治疗
Acute biliary pancreatitis（ABP）
Dampness and heat in liver and gallbladder type
Integrated Chinese and western medicine therapy
Dachaihu tang
Endoscopic interventional treatment
