摘要
目的:通过对近几年来我院就诊的2 048例呼吸系统疾病儿童过敏原体外检测结果的分析,为临床治疗及防治疾病提供参考依据。方法:采用德国Mediwiss公司Allergyscreen Analvtic GmbH过敏原检测系统,对2012年11月至2015年11月来我院就诊的怀疑因过敏引起呼吸系统疾病的2 048例患儿和健康体检儿童104例血清中14种过敏原特异性IgE抗体进行检测,并结合临床资料进行分析。结果:呼吸系统疾病过敏原阳性率最高的是来源于尘螨,其次是猫狗毛皮屑及牛奶;吸入性过敏原以尘螨最高,食入性过敏原则是牛奶最高;男童和女童各组过敏原阳性率差异无统计学意义。4岁以下年龄组的食物过敏原阳性率较高(P<0.05),4岁及以上者则吸入性过敏原阳性率高(P<0.05)。结论:尘螨、猫狗皮屑和牛羊肉是苏皖地区呼吸系统疾病患儿最常见的过敏原。
Objective： Results of in-vitro detection of allergens of 2 048 cases of children with respiratory diseases in Nanjing Children’s Hospital in recent years were analyzed,to provide references for clinical treatment as well as prevention and treatment of diseases. Methods： The allergen detection system Allergyscreen Analvtic Gmb H from Mediwiss（ Germany） was used to perform detection of 14 types of allergen-specific Ig E antibodies in the serum of2 048 cases of children with suspected allergy-caused respiratory diseases in Nanjing Children’s Hospital from November 2012 to November 2015 and 104 cases of children from health examination. Moreover,related data was used to perform analysis. Results： For respiratory allergen diseases,house dust mites had the highest positive rate,dog and cat dander had the second highest,and milk had the third highest. Among inhaled allergens,house dust mites had the highest positive rate,and among ingested allergens,milk had the highest positive rate. Differences in groups of allergens of male children and female children were statistically insignificant. for the children below 4years old,allergens in the food had relatively high positive rates（ P 〈 0. 05）,and for children above 4 years old,inhaled allergens had high positive rates（ P 〈 0. 05）. Conclusion： For children with respiratory diseases in Jiangsu and Anhui districts,house dust mites,dog and cat dander,and beef and mutton were the most common allergens.
出处
《东南大学学报（医学版）》
CAS
北大核心
2016年第6期969-972,共4页
Journal of Southeast University(Medical Science Edition)
