摘要
目的探讨经尿道直出绿激光膀胱壁网状内切开治疗氯胺酮相关性挛缩膀胱与膀胱水扩张术进行对比研究,以评价此方法的安全性与疗效。方法回顾性地分析了2008年1月—2015年12月我院收治的氯胺酮相关性膀胱炎患者32例,其中男23例,女9例,12例行经尿道直出绿激光膀胱壁网状内切开(观察组),20例行膀胱水扩张术(对照组)。在术后6周、1年分别采取O’Leary-Sant的问题评分和尿流动力学检查等的方法对挛缩膀胱治疗前后疗效进行比,观察其恢复情况。结果观察组患者术后膀胱容量较对照组患者膀胱容量明显扩大(P<0.05),观察组术后6周、1年O’Leary-Sant评分与对照组比较,差异均有统计学意义(P<0.05)。结论经尿道直出绿激光膀胱壁网状内切开作为一种新型治疗方法,可有效地治疗氯胺酮相关性膀胱炎,有效的增加膀胱容量,改善LUTS症状。
Objective To explore the role of transurethral front - firing greenlight bladder autoaugmentation for bladder contracture. Methods Between January 2008 and December 2015, thirty - two patients diagnosed with contracted blad- der were all refractory to conservative treatment. Twenty patients in the control group received traditional therapeutic hydrodis- tension of the bladder, while others in the observation group received the treatment of Transurethral Front- firing Greenlight Bladder Autoaugmentationfor Bladder Contracture. The O'Leary- Sant problems scoring and urodynamics examination were conducted before and after operation for disease assessment. Results The bladder capacity of patients in the observation group was much higher than that of patients in the control group ( P 〈 0. 05). The O'Leary - Sant problems scoring of the ob- servation group were significantly improved at six weeks, one year after surgery comared with the control group ( P 〈 0. 05 ). Conclusion Our novel transurcthral front -firing Greenlight bladder autoaugmentation is a safe and effective treatment for contracted bladders. Future studies with larger sample size and long - term follow - up are needed to confirm our findings.
出处
《现代医院》
2017年第4期554-557,共4页
Modern Hospitals
基金
广东省科技计划项目(编号:20140212)
关键词
氯胺酮
挛缩性膀胱
直出绿激光
Ketamine
Contracture Bladder
Front- Firing Greenlight