摘要
目的:探讨血栓通注射液治疗脑出血合并脑梗死缓解期的临床疗效。方法:选取2014年10月—2016年10月收治的68例脑出血合并脑梗死缓解期患者作为研究对象,采用随机数字表法分为观察组和对照组。对照组32例患者给予常规保守疗法,观察组36例患者在对照组基础上加用血栓通注射液,比较两组患者治疗后的血肿体积、血液流变学指标变化情况及临床疗效。结果:治疗1、2周后,两组患者的血肿体积均较治疗第1日显著缩小,且观察组患者血肿缩小程度明显优于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组患者全血高切黏度、全血低切黏度、血浆比黏度、红细胞比容均较治疗前明显降低,且显著低于对照组治疗后,差异均有统计学意义(P<0.05)。观察组患者的总有效率为91.67%(33/36),显著高于对照组的71.88%(23/32),差异有统计学意义(P<0.05)。结论:血栓通注射液治疗脑出血合并脑梗死缓解期,可有效促进血肿吸收,改善血液流变学指标,效果较好,安全性较高。
OBJECTIVE： To probe into the clinical efficacy of Xueshuantong injections in treatment of cerebral infarction complicated with cerebral hemorrhage merger during remission. METHODS： 68 patients with cerebral infarction complicated with cerebral hemorrhage merger admitted from Oct. 2014 to Oct. 2016 were extracted to be divided into observation group and control group via the random number table. 32 cases in control group were given conventional conservative treatment,while the observation group were additionally given Xueshuantong injections based on the control group. The hematoma volume,hemorheology index changes and clinical efficacy of two groups were compared. RESULTS： After treatment for 1 week and 2 weeks,the hematoma volume were significantly reduced compared with the treatment of the 1st day,and the observation group was better than that of control group,with statistically significant difference（ P〈0. 05）. After treatment,the whole blood high shear viscosity,whole blood low shear viscosity,plasma specific viscosity,erythrocyte pressure in observation group decreased significantly compared with before treatment,and were significantly higher than those of control group,with statistically significant difference（ P〈0. 05）. The total effective rate of observation group was 91. 67%（ 33/36）,significantly higher than that of control group[71. 88%（ 23/32） ],with statistically significant difference（ P〈0. 05）. CONCLUSIONS： Xueshuantong injections in treatment of cerebral infarction complicated with cerebral hemorrhage merger during remission can effectively promote the hematoma absorption,alleviate nerve function defect,improve blood rheology indicators and improve the clinical curative effects with high safety.
出处
《中国医院用药评价与分析》
2017年第3期331-333,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
脑梗死缓解期
脑出血
血栓通
血液流变学
Cerebral infarction remission
Cerebral hemorrhage
Xueshuantong
Hemorheology
