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A型肉毒毒素注射治疗腋臭的临床效果 被引量:12

Clinical efficacy of botulinum toxin A injections in treatment of bromhidrosis
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摘要 目的 探讨A型肉毒毒素注射治疗腋臭的临床效果及复发情况.方法 将接受治疗的被诊断为腋臭患者89例分为观察组(42例)和对照组(47例).观察组采用A型肉毒毒素治疗,对照组行腋部小切口手术进行治疗,比较两组术后总有效率、并发症、复发率.结果 治疗3个月后,两组总有效率差异无统计学意义(P>0.05).观察组并发症发生率为2.38% (1/42),对照组并发症发生率为14.89%(7/47),差异有统计学意义(x2=4.245,P<0.05);经过9个月随访,观察组有31例出现腋臭复发,复发率为73.81%,对照组有2例出现腋臭复发,复发率为4.26%,差异有统计学意义(x2=43.21,P<0.05).结论 注射A型肉毒毒素治疗腋臭是一种无创、并发症少、治疗效果较好的方法,但是术后复发率较高,需要多次注射. Objective To investigate therapeutic effect of bromhidrosis by botulinum toxin A injections and situation of bromhidrosis recurrence.Methods Clinical data of bromhidrosis patients were analyzed in our hospital from January 2013 to June 2014.A total of 89 cases were involved in this study and randomized into two groups:observation group (42 cases) were treated by botulinum toxin A,and patients with the control group (47 cases) were treated by small skin excision.The total effective rate,incidence of complications and recurrence rate in both groups were compared.Results After treatment for 3 months,the total effective rate of both group had no statistical difference (P〉 0.05).After different treatment,the incidence of complications in observation group of patients was 2.38% (1/42),and that in the control group was 14.89% (7/47);complication rates of control group patients was significantly higher than that of the observation group,with statistical significance (x2 =4.245,P〈0.05).After 9 months follow-up,31 cases in the observation group of patients showed bromidrosis recurrence,with recurrence rate of 73.81%;2 patients in the control group showed bromidrosis recurrence,with recurrence rate of 4.26%.Log-Rank test showed that recurrence rate in observation group was significantly higher than that of control group (x2 =43.21,P 〈0.05).Conclusions Botulinum toxin A injection is an uninvasive method for the treatment of bromhidrosis with fewer complications and good effect,but the postoperative recurrence rate is higher and it needs injections for many times.
出处 《中华医学美学美容杂志》 2017年第2期79-81,共3页 Chinese Journal of Medical Aesthetics and Cosmetology
关键词 A型肉毒毒素 腋臭 治疗效果 复发率 Botulinum toxin A Bromidrosis Treatment effect Recurrence rate
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