摘要
目的探讨C反应蛋白(CRP)与白蛋白(ALB)比值预测重症肺炎患者预后的临床价值。方法选取2011年1月至2015年12月我院重症监护室收治的150例成人重症肺炎患者作为研究对象,根据治疗效果将所有研究对象分为存活组(107例)与死亡组(43例),对比分析两组患者的临床资料指标。结果存活组年龄、CRP、CRP/ALB比值、CURB-65评分显著低于死亡组,ALB显著高于死亡组,差异有显著性(P<0.05)。两组患者性别、白细胞计数(WBC)、血红蛋白(Hb)、血小板(PLT)、合并高血压、合并糖尿病、合并冠心病,相比差异无显著性(P>0.05)。多因素Logistic回归分析显示,CRP/ALB比值是重症肺炎患者预后不良的独立危险因素指标(P<0.05),年龄、CRP、ALB、CURB-65评分是重症肺炎患者预后不良的非独立危险因素指标(P>0.05)。结论 CRP/ALB比值评估重症肺炎的预后价值优于单独检测CRP、ALB。
Objective To investigate the clinical value of C reactive protein （CRP） and albumin （ALB） ratio in predicting the prognosis of patients with severe pneumonia. Methods 150 adult severe pneumonia patients from January 2011 to December 2015 in intensive care room of our hospital were selected as the research objects. According to the therapeutic effect, all subjects were divided into the survival group （ 107 cases） and the death group （43 cases）. The clinical data of the two groups were compared and analyzed. Results The age, CRP, CRP/ALB ratio and CURB-65 score of the survival group were significantly lower than those in the death group, and ALB was significantly higher in the survival group than in the death group （P 〈 0.05）. Sex, white blood cell count （WBC）, hemoglobin platelet （Hb）, platelet （PLT）, hypertension, diabetes mellitus and coronary heart disease were not sig- nificantly different in the two groups （P 〉0. 05 ）. Multivariate logistic regression analysis showed that the ratio of CRP/ALB was the independent risk factor of poor prognosis in severe pneumonia patients （ P 〈0. 05 ）, and age, CRP, ALB, CURB-65 score were non independent risk factors of poor prognosis in severe pneumonia patients （P〉0. 05 ）. Conclusion The prognostic value of CRP/ALB ratio in patients with severe pneumonia is better than that of CRP and ALB alone.
作者
李娜
刘婧
苗晓云
回志
邱春华
LI Na LIU Jing MIAO Xiao-yun HUI Zhi QIU Chun-hua(Cangzhou People＇s Hospital of Hebei Province, Cangzhou, Hebi 061000, China)
出处
《临床肺科杂志》
2017年第6期1113-1116,共4页
Journal of Clinical Pulmonary Medicine
关键词
C反应蛋白
白蛋白
重症肺炎
预后
C reactive protein
albumin
severe pneumonia
prognosis
