摘要
目的探讨研究麻醉与术后谵妄的相关性。方法选择2015年1月~2016年1月行开胸手术的120例患者为研究对象,随机将其分为试验组和对照组,每组60例。试验组患者麻醉诱导前10 min静脉持续性泵注0.6μg/kg的右美托咪定作为负荷剂量,术中持续泵注0.4μg/kg的右美托咪定,对照组患者泵注相同剂量的生理盐水。两组患者均采用静吸复合全身麻醉。分析麻醉与术后谵妄的关系;研究右美托咪定对术后谵妄的影响。结果麻醉与术后谵妄具有一定相关性,相关系数为r=0.61;试验组术后谵妄发生率低于对照组(P<0.05)。结论麻醉与术后谵妄具有一定相关性;右美托咪定可有效降低术后谵妄的发生率。
Objective To investigate the correlation of anesthesia and postoperative delirium. Methods 120 patients with open chest surgery in our hospital from January 2015 to January 1016, were randomly divided into experimental group and control group, with 60 cases in each group. 10 minutes before induction of intravenous dexmedetomidine infusion of 0.6 !a g/kg pump as a loading dose of anesthesia for patients in the experimental group, 0.4μ g/ kg fixed continuous infusion of dexmedetomidine during operation, patients in the control group had the same dose of saline infusion. Two groups of patients were all used intravenous anesthesia combined with general anesthesia. Analyzed the correlation of anesthesia and postoperative delirium; study the effect of dexmedetomidine on postoperative delirium. Results The anesthesia and postoperative delirium had certain correlation, the correlation coefficient was r= 0.61; the experimental group postoperative delirium incidence rate was lower than that of the control group （P 〈 0.05 ）. Conclusion Anesthesia and postoperative delirium had certain correlation; dexmedetomidine could effectively reduced the incidence rate of postoperative delirium.
出处
《中国处方药》
2017年第5期116-117,共2页
Journal of China Prescription Drug
关键词
麻醉
术后谵妄
相关性
Anesthesia
Postoperative delirium
Correlation
