摘要
目的 :了解外胚层发育不良综合征(ectodermal dysplasia,ED)患者的颌面部发育状况,为临床治疗提供参考。方法:收集2013年6月—2016年10月收治的48例ED患者的临床信息和头颅侧位X线片。将患者分为2组:第1组23例,除缺牙外,累及≥2种外胚层组织;第2组25例,除缺牙外,仅累及1种外胚层组织。比较2组病例的缺牙数及颌面骨形态影像学参数的差异。采用SPSS 17.0软件包对数据进行单样本t检验和成组t检验。结果:第1组缺牙数显著多于第2组(22.3±5.8∶12±6.6,P<0.05)。在女性患者中,第1组滞留乳牙数显著多于第2组(8±4∶2.4±2.7,P<0.05)。2组患者的上颌骨长度减少(ANS-Ptm减小)且位置后缩(S-Ptm、SNA、NA-PA减小),下颌骨前突(NP-FH增大)、颏部前突(Y轴角减小),下颌骨长度(Co-Po)及位置(S-Co)相对正常,骨性Ⅲ类错(ANB<0),全面高降低(NMe减小)。在男性患者中,第1组较第2组的SNA、NA-PA、ANS-Ptm、S-Ptm、Y轴角显著减小(P<0.05),NP-FH显著增大(P<0.05)。结论:ED患者颌面骨形态表现为上颌骨长度减少及位置后缩,下颌骨长度和位置相对正常,下颌骨前突、颏部前突、骨性Ⅲ类错和全面高降低。ED患者颌面骨形态异常的严重程度与缺失的恒牙数呈正相关,滞留的乳牙可能会促进颌面骨发育。
PURPOSE： The study was performed to analyze the maxillofacial morphology of 48 patients with ectodermal dysplasia （ED） and to provide some reference for implant treatment of ED patients. METHODS： The study collected the clinical data and lateral cephalometric radiographs of 48 patients with ED treated between June 2013 and October 2016. The patients were grouped as follows： group 1, 23 patients, at least with two kinds of ectodermal disorder, besides hypodontia; group 2, 25 patients, only with one kind of ectodermal disorder, besides hypodontia. The number of missing teeth and maxillofacial cephalometric parameters were compared between 2 groups. SPSS 17.0 software package was performed for statistical analysis. RESULTS： The number of missing teeth was significantly larger in group 1 （22.3±5.8） than group 2 （12± 6.6） （P〈0.05）. The number of retained deciduous teeth was significantly larger in group 1 （8±4） than in group 2 （2.4±2.7） in females （P〈0.05）. Cephalometric analysis showed a reduced maxilla length （ANS-Ptm）, retrusive maxilla （S-Ptm, SNA, NA-PA）, a normal size （S-Co） and length （Co-Po） of mandible, a protruding mandible （NP-FH） and chin （Y axis）, skeletal Angle Ⅲmaloeclusion（ANB〈0） and a reduced facial height （N-Me） in two groups. SNA, NA-PA, ANS-Ptm, S-Ptm and Y axis were significantly decreased and NP-FH was significantly increased in group 1 compared to group 2 in males （P〈0.05）. CONCLUSIONS： Maxillofacial morphology of ED patients typically presented a reduced maxilla length and retrusive maxilla, a normal size and length of mandible, a protruding mandible and chin, skeletal Angle Ill malocclusion and a reduced facial height. The severity of abnormalities in maxillofacial hone morphology was correlated positively with absence of permanent teeth. Furthermore, retained deciduous teeth might have positive effect on the developmenl of maxillofacial bone.
出处
《上海口腔医学》
CAS
CSCD
2017年第2期193-197,共5页
Shanghai Journal of Stomatology
基金
国家自然科学基金(81371190)
上海交通大学医工交叉重点项目(YG2016ZD01)
上海交通大学医学院附属第九人民医院融合课题
