摘要
目的研究负荷量波立维和阿司匹林在脑梗死急性期中的临床应用效果。方法选取该院2014年2月‐2016年7月治疗的脑梗死急性期患者120例为研究的对象,依据治疗方法的不同将其分为联合治疗组(负荷量波立维+阿司匹林)和阿司匹林组,比较两组患者治疗效果与不良反应发生情况。结果联合治疗组临床治疗效果总有效率为88.33%(53/60),显著高于阿司匹林组的68.33%(41/60)(P<0.05);未接受治疗前,组间患者美国国立卫生研究院卒中量表(NIHSS)评分比较差异无统计学意义(P>0.05);经不同方法治疗后,联合治疗组患者的NIHSS评分可显著低于阿司匹林组患者(P<0.05);两组患者均未见有严重的颅内及心脏出血等严重并发症。结论负荷量波立维和阿司匹林联合在脑梗死急性期中的治疗有疗效,可促进患者快速康复,具有积极的临床应用价值。
[Objective]To investigate the efficacy of loading dose of plavix and aspirin for patients with acute cerebral infarction.[Methods]Totally 120 cases of acute cerebral infartion patients hospitalized in our hospital from February 2014 to July2016 were selected as research subjects.All patients were randomly divided into combined treatment group（loading dose of plavix and aspirin） and aspirin group according to different methods of treatment.The therapeutic effects and adverse reactions of the two groups were compared.[Results]The total effective rate in treatment group（88.3%） was significantly higher than that of aspirin group（68.3%）（P〈0.05）;before treatment,the difference in the NIHSS（National Institute of Health Stroke Scale） score between the two groups was not statistically significant（P〉0.05）;after receiving different treatments,the NIHSS scores were significantly decreased in both two groups（P〈0.05）,meanwhile the NIHSS score of the combination group was significantly lower than that of aspirin group（P〈0.05）;No severe intracranial or heart bleeding or other severe complications occurred in two groups of patients.[Conclusion]For patients with acute cerebral infarction,loading dose of plavix and aspirin can effectively improve the therapeutic effect.
出处
《中国医学工程》
2017年第3期71-73,共3页
China Medical Engineering
