摘要
性传播疾病(sexually transmitted diseases,STDs)是一组主要通过人类性行为传播、严重危害人类身心健康的传染病,并已成为全球普遍关注的公共卫生问题。近年全球年新增STDs病例居高不下,其重要原因之一是由于STDs病原菌耐药性增加使得治疗变得困难。了解STDs病原菌的耐药机制和抗生素作用机制对于修正现有的药物和开发新的治疗药物十分必要。简述了4种常见的STDs及其治疗药物,并对常见病原菌的耐药性进行了概述。
Sexually transmitted diseases （STDs） are a varied group of infections that usually are passed from person to person by sexual contact. STDs have become the major concern for public health systems worldwide for their serious harmfulness to the physical and mental health of people, due to their＇ s ascending tendency in recent years. Increasing drug resistance involved in bacteria causing STDs makes treatment be more difficuh. It is necessary to modify existing drugs and to develop new ones directed against new targets that a detailed understanding of the mechanisms of antimicrobials action and the emergence of resistance is critical. Firstly, we describe the most common STDs, and the corresponding antibiotics used for their treatment. Then, a brief introducion focuses on the relevant antimicrobial resistance mechanisms.
出处
《微生物学免疫学进展》
2017年第2期78-82,共5页
Progress In Microbiology and Immunology
基金
国家自然科学基金项目(81273322
81373230)
湖南省教育厅创新平台开放基金(湘教财指[2015]54号)
湖南省教育厅资助科研项目(15C1256)
湖南省分子靶标新药研究协同创新中心(湘教通[2014]405号)
关键词
性传播疾病
抗生素
耐药机制
Sexually transmitted diseases （STDs）
Antibiotic
Antimicrobial resistance
