摘要
目的探讨老年患者24 h动态血压监测及血压变异性(blood pressure variability,BPV)与踝臂指数(ankle-brachial index,ABI)之间的相关性。方法选择于2014年1月至2015年8月来广州市番禺区中心医院就诊的65~80岁老年患者220例,按照ABI数值将所有老年人分为正常ABI组(ABI>0.9)和异常ABI组(ABI≤0.9或ABI>1.3),其中正常ABI组121例,异常ABI组119例。比较两组患者24 h动态血压参数和BPV参数。按照血压高低将患者分为高血压组(95例)和非高血压组(125例),分析比较两组BPV参数及ABI差异。采用Logistic回归分析法分析ABI的独立危险因素。结果高血压组24 h收缩压BPV、夜间收缩压BPV明显高于非高血压组,差异有统计学意义(P<0.05)。异常ABI组24 h舒张压、白天舒张压、夜间舒张压、24 h收缩压BPV明显低于正常ABI组,夜间收缩压BPV明显高于正常ABI组,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,夜间舒张压、夜间收缩压BPV是ABI的独立危险因素。结论老年患者的舒张压、夜间舒张压、夜间收缩压BPV是影响ABI的独立危险因素,BPV与ABI明显相关,平稳控制血压对延缓动脉硬化的发生有一定影响。
Objectives To investigate the 24 h ambulatory blood pressure monitoring and analyze the correlation between ankle-braehial index （ABI） with blood pressure variability （BPV） in elderly patients. Methods We selected 220 old patients with age from 65 to 80 years old treated in Panyu Central Hospital from January 2014 to August 2015. According to the value of ABI, all the elderly patients were divided into normal ABI group （ABI〉0.9） and abnormal ABI group （ABI 〈 0.9 or ABI〉1.3） , 121 patients in normal ABI group and 119 patients in abnormal ABI group. 24 h ambulatory blood pressure parameters and BPV parameters of the two groups were eompared. Aeeording to the blood pressure level, the patients were divided into hypertension group （95 cases） and non-hypertension group （125 cases）. BPV parameters and ABI differences were compared between the the two groups. Logistic regression analysis was used to analyze the independent risk factors of ABI. Results Level of 24 h systolic blood pressure BPV （SBPV） and night SBPV in patients with hypertension were significantly higher than those in non-hypertension group, and the difference was statistically significant （P〈0.05）. Levels of 24 h diastolic blood pressure （DBP）, day DBP, night DBP, 24 hSBP~ in abnormal ABI group were significantly lower than those in normal ABI group, the night SBPV level was significantly higher than that in normal ABI group, the differences were statistically significant （P〈0.05）. Logistic regression analysis showed that night DBP and night SBPV were the independent risk factors of ABI. Conclusions DBP, night DBP and night SBPV of old patients are independent risk factors of ABI, and the BPV significantly correlate with ABI. Stably controlling of blood pressure has a certain effect on delaying the occurrence of atherosclerosis.
出处
《岭南心血管病杂志》
2017年第2期194-196,223,共4页
South China Journal of Cardiovascular Diseases
关键词
高血压
危险因素
动脉粥样硬化
踝臂指数
血压变异性
hypertension
risk factors
atherosclerosis
ankle brachial index
blood pressure variability
