摘要
目的:观察不同病原体致小儿呼吸道感染后血白细胞计数(white blood cell count,WBC)、C反应蛋白(c-reactive protein,CRP)以及降钙素原(procaicltonin,PCT)临床变化。方法:选择2015年1月至2016年5月我院儿科收治的呼吸道感染患儿共157例,按照病原体的不同,分为细菌组、病毒组以及支原体组,细菌组按照染色不同,再次分为G+组以及G-组。分析各组患儿WBC、CRP以及PCT的结检测结果和治疗前后的变化情况,初步提供病原学分类诊断依据。结果:发现细菌组的WBC、CRP以及PCT均较支原体组以及病毒组显著升高(P<0.05),而病毒组以及支原体组间的WBC、CRP以及PCT均无显著性差异。发现G+组的WBC以及CRP与G-组无显著性差异(P>0.05),而G+组的PCT较G-组显著升高(P<0.05)。PCT对细菌小儿呼吸道细菌性感染的诊断准确率率显著高于WBC以及CRP(P<0.05)。PCT诊断小儿呼吸道细菌性感染具有高特异性以及低假阳性率。结论:WBC、CRP以及PCT检测可初步判断不同病原体致小儿呼吸道感染,对于细菌性感染,PCT的诊断价值要优于WBC以及CRP。
Objective：To observe the clinical variety of white blood cell count （WBC）, C-reactive protein （CRP） and procalcitonin （PCT） of different pathogens causing respiratory infection in children.Methods： 157 cases of children of respiratory infections in our hospital were chose from January 2015 to May 2016, according to different pathogens, divided into bacteria group, viruses group and mycoplasma group, according to different staining of bacteria groups, divided group G＋ and group G-.Analysis of the WBC, CRP and PCT test results and the change of each group before and after the treatment was conducted;a preliminary classification of etiology diagnosis basis was provided.Results： The WBC, CRP and PCT in found bacteria group were significantly increased the mycoplasma group and virus group （P 〈 0.05）, while the WBC, CRP and PCT between virus group and mycoplasma group were no significant difference.WBC and CRP on group G＋ and G-group, there was no significant difference （P 〉 0.05）, but PCT on G＋ group is significantly increased than G-group （P 〈 0.05）.Diagnosis accuracy rate of PCT on children respiratory tract bacterial infection is significantly higher than the WBC and CRP （P 〈 0.05）.The diagnosis of respiratory tract bacterial infection in children by PCT had high specificity and low false positive rate.Conclusion： The WBC, CRP and PCT test can preliminary judgment different pathogens to children respiratory infection, for bacterial infections, the diagnostic value of PCT is superior to the WBC and CRP.
出处
《河北医学》
CAS
2017年第4期561-564,共4页
Hebei Medicine
基金
湖北省自然科学基金重点项目,(编号:2010CDA033)
关键词
病原体
呼吸道感染
C反应蛋白
降钙素原
Pathogens
Respiratory infections
C-reactive protein
Procalcitonin
