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腹腔镜阑尾切除术治疗急性阑尾炎的临床疗效及其安全性评价 被引量:88

Analysis and Safety Evaluation of the Clinical Efficacy of Laparoscopic Appendectomy for Acute Appendicitis
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摘要 目的探讨腹腔镜阑尾切除术手术治疗急性阑尾炎患者临床疗效分析及其安全性.方法纳入的92例急性阑尾炎患者,随机数字表法随机分为观察组(n=46)与对照组(n=46).观察组给以腹腔镜阑尾切除术治疗,对照组以传统开腹阑尾切除术治疗.比较2组术中情况、术后情况及术前、术后1 d和3 d WBC水平变化.结果观察组手术时间短于对照组(t=4.049,P<0.05),淋巴结比较差异无统计学意义(t=0.570,P>0.05),出血量少于对照组(t=20.748,P<0.05);观察组下床活动时间快于对照组(t=9.221,P<0.05),进食时间快于对照组(t=8.794,P<0.05),肛门恢复排气时间快于对照组(t=17.423,P<0.05),住院时间短于对照组(t=13.479,P<0.05),并发症发生率低于对照组(t=13.883,P<0.05);观察组术后1 d和3 d WBC水平均低于术前(t分别=7.277、26.911,P<0.05);观察组术后1 d和3 d WBC水平均低于同期对照组(t分别=3.6189、17.827,P<0.05);观察组术后3 d WBC水平低于术后1 d(t=20.732,P<0.05).结论腹腔镜阑尾切除术治疗急性阑尾炎患者临床疗效显著,是一种安全、有效的治疗方法,值得临床进一步研究. Objective To investigate the clinical efficacy and safety of laparoscopic appendectomy for acute appendicitis. Me thods Nighty- two cases of acute appendicitis were included in this study, randomly divided into observation group(n =46) and control group(n =46) according to the random number table method. The observation group was treated with laparoscopic appendectomy, and control group with the traditional open appendectomy treatment. We compared the two groups of cases in postoperative conditions and the level of WBC changes and 1d and 3d after operation. Re s ults The operation time of the observation group was shorter than that of the control group(t =4.049, P 〈0.05); there was no significant difference in lymph nodes(t =0.570, P 〉0.05);the amount of bleeding was less than that of the control group(t=20.748, P〈0.05). The get- out- of- bed activity time in the observation group was faster than the control group(t=9.221,P〈0.05); eating time was faster than the control group(t=8.794,P〈0.05);the anus recovery exhaust time was faster than the control group(t=17.423,P〈0.05);hospital stay was shorter than the control group(t=13.479,P〈0.05);the complication rate was lower than that of the control group(t=13.883,P〈0.05). The levels of 1d and 3d WBC were lower in the observation group than that in the preoperative group(t=7.277,26.911,P〈0.05);the levels of 1d and 3d WBC in the observation group were lower than those in the control group at the same time(t =3.6189, 17.827, P 〈0.05);the 3d WBC level of the observation group was lower than that of 1d(t=20.732,P〈0.05). Conclus ion Laparoscopic appendectomy is a safe and effective treatment for patients with acute appendicitis, and it is worthy of further clinical research.
作者 潘子鹏 李闻 PAN Zi-peng LI Wen(Dept. of Surgery, People's Hospital of Baoting County, Baoting Hainon 572300 Dept. of GI Medicine, Hainan Branch of PLA General Hospital, Sanya Hainan 572013, China)
出处 《昆明医科大学学报》 CAS 2016年第8期119-122,共4页 Journal of Kunming Medical University
基金 海南省卫生厅医学科学研究基金资助项目(琼卫2013重点-13号)
关键词 腹腔镜阑尾炎切除术 急性阑尾炎 疗效 安全性 Laparoscopic appendectomy Acute appendicitis Efficacy Safety
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