摘要
报告1例儿童寻常性银屑病并发继发性血小板增多症。患儿男,7岁。躯干及四肢散在分布红斑、鳞屑1个月,血常规示血小板1654×109/L。皮肤科检查:躯干及四肢散在分布黄豆至硬币大炎性红斑,表面附着银白色鳞屑,刮除后可见薄膜现象和Auspitz征阳性。皮损组织病理检查:表皮角化不全,角质层可见Munro微脓肿,颗粒层变薄,部分消失,棘层肥厚,部分呈棒槌状伸入真皮;真皮浅层毛细血管扩张及炎性细胞浸润。诊断:寻常性银屑病并发继发性血小板增多症。予口服消银颗粒,外用地奈德乳膏及卡泊三醇软膏治疗后皮损消退,血小板下降明显。
A case of psoriasis vulgaris with secondary thrombocytosis in a child is reported. A 7- year-old boy presented with erythemas and scales on the trunk and limbs for one month. Routine blood test showed 1654×10^9/L of platelet counts. Physical examination revealed soybean to coin sized inflammatory erythemas with silver scales on the trunk and limbs. After removal of scales, the underneath skin had a smooth glossy red membrane, and Auspitz sign was positive. Histopathologieal examination showed parakeratosis, Munro abscesses in the horny layer, granular layer thinning with partial disappearance, acanthosis, partial extension of rete ridges in wooden club shape into the dermis, and dilated blood vessels and inflammatory infiltrate in the superficial dermis. The diagnosis was psoriasis vulgaris with secondary thrombocytosis. The lesions resolved and platelet counts declined markedly after treatments with Xiaoyin granules, desonide and ealcipotfiol.
出处
《临床皮肤科杂志》
CSCD
北大核心
2017年第5期359-361,共3页
Journal of Clinical Dermatology
基金
河北省政府资助临床优秀人才培训基金(361037)资助项目
