摘要
目的 :观察嗜酸乳杆菌 (乐托尔 )对人胃内幽门螺杆菌的治疗作用。方法 :经证实 Hp感染阳性的胃、十二指肠溃疡病人 ,分别给予嗜酸乳杆菌治疗组与胃三联的对照组 ,给药后观察临床症状恢复情况 ,溃疡愈合情况 ,胃粘膜 Hp感染情况 ;结果 :(1)总的临床症状改善率治疗组总有效率为 89.8% (35 / 37) ,对照组为 92 .9% (34/ 36 ) ,两组比较差异无显著性。 (2 )溃疡愈合率 :两组病人愈合治疗组与对照组分别是85 .9% (5 5 / 6 4 )和 92 .1% (71/ 77) ,两组χ2 检验比较差异无显著性 (P<0 .0 5 )。 (3) Hp转阴率 :两组在 4周末分别是治疗组 6 7.3% (33/ 4 9)和 84 .5 % (49/ 5 8) ,两组比较差异无显著性 (P>0 .0 5 )。结论 :嗜酸乳杆菌在抑制 Hp感染作用与抗菌素相仿 ,值得临床上应用 ,是临床上抗 Hp感染治疗极的前途的药物之一。
Objective:To observe the therapeutical effect Lactobacillus for Helicobacter pylori Methods:The patients of Hp positive were deprived two groups(treatment group:Lacteolfort1 packet,bid,+Omeprazole 20 mg,gd,+Sucralfate 1 0,tid,course for 4 w) and contrast group (Omeprazole 20 mg,gd,+Metronidazole 0 4 g,tid+Amoxicillin 0 5,tid+Sucralfate 1 0,tid, course for 4 w)?and then it were observed:(1) Clinical symptom recovery;(2)Gastric mucosa Hp infection;(3)Ulcer healing conditions;Result:(1)Clinical symptom amelioration:therapeutics group were 89 9%(35/37) and contrast 92 6%(34/36),it was not significant differently?(2)Ulcer healing rate:LB group were 85 9%(55/64) and contrst 92 1%(71/77)(P>0 05);(3)Hp infection rate:two groups were differently 67 3%(33/49) and 84 5%(49/58) Conclusion:The study suggested LB had a significantly effect on anti Hp infection It is on of the most future drugs in clinical anti Hp infection therapectic
出处
《中国微生态学杂志》
CAS
CSCD
2002年第3期163-164,共2页
Chinese Journal of Microecology
