摘要
目的 分析腹腔镜与开腹胃楔形切除术治疗胃间质瘤（GIST）患者的临床疗效及安全性.方法 抽取2014年3月至2015年64例GSIT患者,根据手术方式不同分为对照和研究组,每组32例.研究组行腹腔镜胃楔形切除术,对照组实施开腹手术,术后1年对两组患者进行随访.对比两组围术期相关指标水平、营养状况相关指标（前白蛋白、转铁蛋白、白蛋白）水平变化情况,并统计两组并发症发生率及疾病复发率.结果 研究组住院时间、切口长度、术中出血量、术后摄食时间、肛门排气时间均明显少于对照组,差异有统计学意义（P〈0.05）,两组手术用时比较差异未见统计学意义（P〉0.05）;术前两组前白蛋白、转铁蛋白、白蛋白水平比较差异未见统计学意义（P〉0.05）,术后研究组前白蛋白[（0.11±0.04）g/L]、转铁蛋白[（0.65±0.29）g/L]明显高于对照组[（0.06±0.03）、（0.48±0.28）g/L],差异有统计学意义（P〈0.05）;研究组并发症发生率（12.51%）明显低于对照组（43.76%）,差异有统计学意义（P〈0.05）;研究组疾病复发率（3.13%）与对照组（6.25%）比较差异未见统计学意义（P〉0.05）.结论 采用腹腔镜胃楔形切除术治疗胃间质瘤效果显著,创伤小、手术用时及术后机体功能康复用时较少,可改善术后营养状况,且并发症发生率较低,远期预后较好,值得推广运用.
Objective To analyze the clinical efficacy and safety of laparoscopic and open gastric wedge resection in the treatment of gastric stromal tumors（GIST）.Methods Sixty-four patients with GSIT from August 2015 to March 2014 were divided into control group（n=32） and study group（n=32） according to the different operation methods.The study group underwent laparoscopic gastric wedge resection, the control group was treated by open surgery.And 1 years after surgery, both groups of patients were followed up.The perioperative indicators related to the level of nutritional status indicators（pre albumin, transferrin, albumin） level changes, and statistics of the two groups of complications and disease recurrence rate was compared.Results The study group of hospitalization time, bleeding volume, incision length, postoperative feeding time, anal exhaust time were significantly less than those of the control group, the differences were significant（P〈0.05）;the operation time had no significant difference between the two groups（P〉0.05）;The prealbumin, transferrin, albumin level had no significant difference between the two groups before operation（P〉0.05）, the postoperative prealbumin [（0.11±0.04） g/L], transferrin [（0.65±0.29） g/L] in study group were significantly higher than those in the control group [（0.06±0.03）, （0.48±0.28） g/L], the differences were significant（P〈0.05）;The complication rate（12.51%） in the study group was significantly lower than that in the control group（43.76%）, and the difference was significant（P〈0.05）;The recurrence rate had no significant difference between the two groups（P〉0.05）.Conclusions Laparoscopic gastric wedge resection for gastric stromal tumors is significant, it has small trauma, operation time and with less postoperative functional rehabilitation and can improve the nutritional status after surgery, and a lower incidence of complications, the prognosis is good, it is worthy of promotion.
出处
《中国实用医刊》
2017年第7期42-45,共4页
Chinese Journal of Practical Medicine
关键词
腹腔镜
开腹
胃楔形切除术
胃间质瘤
Laparoscopy
Laparotomy
Wedge resection of stomach
Gastric stromal tumor
