摘要
目的分析肿瘤患者化疗期间红细胞悬液输注的疗效,为临床化疗方案决策提供参考。方法回顾性分析华西医院2012~2013年住院肿瘤患者化疗期间红细胞悬液输注情况。结果未化疗组肿瘤患者输注红细胞悬液的有效率77.3%(58/75)略高于化疗组75.8%(141/186),但差异无统计学意义(P﹥0.05);经含铂方案化疗的肿瘤患者输注红细胞悬液有效率27.8%(22/79)明显低于非含铂方案化疗组41.1%(44/107),且差异有统计学意义(P<0.05)。结论化疗会降低红细胞悬液输注疗效,含铂化疗药物对骨髓有抑制反应,大大降低肿瘤患者红细胞悬液的输注疗效。
Objective To investigate, so as to provide reference for clinical decision about chemotherapy regimens. To provide reference for clinical decision about chemotherapy regimens, we studied the curative effect of red blood cells infusion on tumor patients undergoing chemotherapy. Methods Retrospectively we analyzed red blood cells infusion of hospitalized tumor patients during chemotherapy in West China Hospital of Sichuan University from 2012 to 2013. Results Tumour patient transfusion of red blood cell suspension effective rate was 77.3% （ 58/75） is slightly higher in Chemotherapy group than that 75.8% （141/186） in nonchemotherapy group, but there is no statistical difference （P〉0.05） ： The effective rate of transfusion of red blood cell suspension was （27.8% 22/79） significantly lower in platinumbased chemotherapy of tumor patient group than that in the nonplatinum-based chemotherapy group （41.1%,44/107 ） , and the difference was statistically significant （P〉0.05 ） .Conclusion Chemotherapy can reduce the curative effect of red blood cells infusion, and platinum-based chemotherapy drugs also cause bone marrow inhibition reaction, which reduce the curative effect of red blood cells infusion in tumor patients.
出处
《临床输血与检验》
CAS
2017年第2期129-131,共3页
Journal of Clinical Transfusion and Laboratory Medicine
关键词
肿瘤
化疗
输血疗效
含铂化疗药物
Tumor Chemotherapy Effect of blood transfusion Platinum-based chemotherapy
