摘要
生物体特定组织或器官内重金属含量可反映环境重金属污染水平,但不能够提供分子水平的信息。生物标志物的变化可用于评估重金属暴露水平及对生物的潜在不利影响。生物标志物包括暴露标志物、效应标志物和易感性标志物。综述了水生动物抗氧化生物标志物、遗传毒性标志物、乙酰胆碱酯酶、金属硫蛋白和热休克蛋白等几种生物标志物监测水体镉污染的原理和应用现状,可为研究镉对水生动物的毒害机制提供参考,为防控重金属污染、保护水生生态系统提供理论依据。
The content of heavy metals in a certain tissue or organ of an organism may reflect the level of heavy metal pollution in the environment,but not any information of molecular level. Changes in biomarkers may be used for assessing level of heavy metal exposure and potential adverse effects on living organisms. Biomarkers can be sorted into three major categories： exposure biomarkers,effect biomarkers and susceptibility biomarkers. Principles for using antioxidant,genetic toxicity,acetyl cholinesterase,metallothionein and heat shock proteins biomarkers to monitor Cd pollution of water bodies,and status of their applications are addressed,in an attempt to provide some reference for future studies on mechanism of cadmium toxication of aquatic animals as well as a theoretical basis for prevention and control of heavy metal pollution and protection of the aquatic ecosystem.ZHOU Ke-xin2 （ 1. School of Applied Meteorology, Nanjing University of Iniormation Science ＆ Technolog^f, Nanjing 210044,China; 2. Nanjing Institute of Environmental Sciences,Ministry of Environmental Protection, Nanjing 210042, China）
出处
《生态与农村环境学报》
CAS
CSCD
北大核心
2017年第4期297-307,共11页
Journal of Ecology and Rural Environment
基金
国家环境保护公益性行业科研专项(201309049)
关键词
重金属
镉
水生动物
生物标志物
heavy metal
cadmium
aquatic animal
biomarker
