摘要
目的:探讨不同绒毛膜性质双胎的临床特征及选择性胎儿生长受限的高危因素。方法:将460例双胎妊娠病例分为单绒毛膜组和双绒毛膜组,对两组相关临床特征进行比较,并通过Logistic回归分析选择性胎儿生长受限发生的高危因素。结果:(1)单绒毛膜双胎组和双绒毛膜双胎组在产妇年龄、受孕方式、分娩方式上差异存在显著性(P<0.05);(2)两组病例未足月胎膜早破及选择性胎儿生长受限发生几率差异存在显著性(P<0.05);(3)两组病例的新生儿体重(大、小)、新生儿转科率差异存在显著性(P<0.05);(4)Logistic回归分析显示:分娩孕周及新生儿体重为危险因素。结论:(1)胎盘的"绒毛膜性质"对孕产妇的妊娠过程及结局有着重要的影响;(2)"单绒毛膜性"是选择性胎儿生长受限的高危因素,即选择性胎儿生长受限的主要病因可能来源于胎盘,其应为一种"胎盘源性疾病"。
Objective To explore the clinical characteristics of monoehorionic or diehoriooie twin pregnancy and the high-risk factors for selective intrauterine growth restriction. Methods 460 women with twin pregnancy were divided into a monoehorionic group and a dichorion group. The related clinical features were compared between the two groups. Logistic regression was used to analyze the high- risk factors for selective intrauterine growth restriction. Results The maternal age, conception way, and mode of delivery differed significantly between the two groups （P 〈 0.05）. There were significant differences in the rates of selective intrauterine growth restriction and preterm premature rupture of membranes （P 〈 0.05）. The neonatal weight （large or small） and the rate of neonatal transfer differed significantly （P 〈 0.05）. Logistic regression showed that gestational age and birth weight were the risk factors. Conclusions The chorionic nature plays an important role in the process and outcomes of maternal pregnancy. Monoehorionic pregnancy is a high risk factor for selective intrauterine growth restriction, meaning the major cause of selective intrauterine growth restrictioo may originate from the placenta, with should be a ＂placenta-derived disease＂.
出处
《实用医学杂志》
CAS
北大核心
2017年第7期1098-1102,共5页
The Journal of Practical Medicine
基金
中美联合发育缺陷转化医学中心建设(2015年度省协同创新与平台建设专项基金)(编号:2015B050501006)
