摘要
以葡萄糖为模板分子,通过电聚合邻苯二胺,在多壁碳纳米管修饰的GC电极表面制备了一种对葡萄糖具有选择性响应的分子印迹聚合薄膜传感器,优化了制备方法。通过循环伏安法(CV)和交流阻抗法对该分子印迹传感器对葡萄糖的响应性能进行了表征。在最优实验条件下,该印迹电极能在6.0~560.0μmol/L浓度范围内对葡萄糖进行检测,检出限为8.0×10^(-7) mol/L,并可在其他物质存在下选择性识别葡萄糖。此传感器可用于血液中葡萄糖的测定,加标回收率为98.5%~103.3%。
A molecularly imprinted polymers membrane sensor for glucose detection was constructed by electropolymerization of o-aminophenol (OAP) on the glassy carbon (GC) electrode surface coated with multi-walled carbon nanotubes (MWCNTs) in the presence of template glucose. The molecularly imprinted sensor was characterized by cyclic voltammetry (CV) and AC impedance method. On the optimal experimental conditions, the molecularly imprinted electrode could selectively detect glucose in the analysis concentration range of 6.0-560.0 μmol/L, with a detection limit of 8.0 × l0^-7 mol/L. The prepared sensor was successfully used to detect glucose in blood. The recoveries were increasing from 98.5% to 103.3%.
出处
《广州化学》
CAS
2017年第2期20-25,共6页
Guangzhou Chemistry
基金
广东省医学科学技术研究基金(A2014181)
关键词
碳纳米管
分子印迹
传感器
葡萄糖
multi-walled carbon nanotube
molecular imprinting
sensor
glucose