摘要
回顾分析1例以发热、胸水为首发症状的慢性粒细胞白血病的临床病理特征。胸水涂片结合细胞块免疫组化考虑髓系肿瘤。基因检测:BCR-ABL1融合基因ABL1激酶区发生E279K突变。骨髓检查:CML(急变期)。胸水中能够及时发现白血病细胞对于临床判断疾病的进展和调整治疗方案有重要价值。
A case of chronic myeloid leukemia with fever and hydrothorax as the first symptom is to be retrospectively analyzed. M yeloid tumor was considered with pleural effusion combined with cell mass immunohistochemistry. Gene detection： E279 K mutation emerges in BCR-ABL1 fusion gene in ABL1 kinase region. Bone marrowexamination： CM L（ acute period）. Timely discovery of leukemia cells in hydrothorax has important value for the progress in clinical judgment of disease and the adjustment of treatment plan.
出处
《浙江医学教育》
2017年第2期62-63,共2页
Zhejiang Medical Education
关键词
慢性粒细胞白血病
发热
胸水
细胞块
免疫细胞化学
chronicmyelogenousleukemia
fever
hydrothorax
cell block
immunohistochemistry
