摘要
目的探讨保留肾单位手术(NSS)治疗老年局限性肾癌患者的安全性和疗效。方法回顾性分析2013年1月-2014年6月76例老年局限性肾癌患者行NSS的临床资料,观察比较手术并发症及治疗前后肾功能的变化。结果 76例患者手术均成功,术后均未发生严重并发症。术后随访14~33个月,平均21个月,仅1例患者于术后12个月局部复发改行根治性肾切除术。术前与术后24 h、术后3、6、12和18个月血清肌酐、尿素氮比较差异均无统计学意义(P>0.05)。术前与术后3、6、12和18个月肾小球滤过率比较差异无统计学意义(P>0.05)。结论 NSS治疗老年局限性肾癌患者安全有效,NSS有助于肾脏功能的保护,尤其适用于老年局限性肾癌患者。
Objective To investigate the safety and effect of nephron-sparing surgery for localized renal cell carcinoma in elderly patients. Methods A total of 76 elderly patients with renal cell carcinoma underwent nephronsparing surgery from January 2013 to June 2014. Their clinical data were retrospectively analyzed. The changes of renal function before and after treatment were observed and compared. Results The operation was performed successfully in all the 76 cases. No serious complications occurred after surgery. The postoperative follow-up ranged from 14 to 33 m with a mean of 21 m. Only 1 case underwent radical nephrectomy because of local recurrence 12 m after operation. Compared to the preoperative level, there was no significant difference in serum creatinine or urea nitrogen level 24 h, 3 m, 6 m, 12 m and 18 m after operation （P 〉 0.05）. The glomerular filtration rate was not significantly different before and after operation （P 〉 0.05）. Conclusions Nephron-sparing surgery is safe and effective for the treatment of renal cell carcinoma and especially indicated for elderly patients with localized renal cell carcinoma.
作者
梁涛
李作为
胡晓勇
田斌强
燕东亮
傅强
Tao Liang Zuo-wei Li Xiao-yong Hu Bin-qiang Tian Dong-liang Yan Qiang Fu(Department of Urology, the Sixth People ＂s Hospital Affiliated to Shanghai Jiao Tong University, ShangHai 200233, Chin)
出处
《中国现代医学杂志》
CAS
北大核心
2017年第7期103-106,共4页
China Journal of Modern Medicine
基金
浦东新区科技发展基金(No:PKJ2014-Y07)
关键词
肾肿瘤
保留肾单位手术
老年患者
kidney neoplasm
nephron-sparing surgery
gerontal patient
