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输尿管软镜与经皮肾镜在治疗肾结石的安全性及疗效的对比性研究 被引量:7

Comparison study on security and curative effect of flexible ureteroscope and percutaneous nephrolithotomy in the treatment of kidney stone
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摘要 目的比较输尿管软镜与经皮肾镜对治疗肾结石的安全性及临床疗效。方法 200例肾结石患者,按随机数字表分为观察组与对照组,每组100例。观察组患者应用输尿管软镜碎石术治疗,对照组患者应用经皮肾镜碎石术治疗。比较两组患者的围术期临床指标及结石清除率,评估两种术式的安全性及临床治疗效果。结果观察组患者术后1 d及3 d血清尿素氮(BUN)、肌酐(Cr)指标低于对照组患者,差异有统计学意义(P<0.05)。观察组患者术中出血量、结石清除率、住院时间、住院费用及术后感染率分别为(6.17±1.38)ml、95.00%、(4.15±1.02)d、(3327.40±415.70)元、3.00%,均优于对照组的(25.33±6.41)ml、87.00%、(7.36±2.08)d、(4238.00±544.30)元、10.00%,差异有统计学意义(P<0.05)。结论临床应用输尿管软镜与经皮肾镜治疗肾结石,输尿管软镜治疗方法在结石清除率、术中出血量、住院时间等指标方面优于经皮肾镜治疗,值得临床广泛推广应用。 Objective To compare the security and curative effect of flexible ureteroscope andpercutaneous nephrolithotomy in the treatment of kidney stone. Methods A total of 200 kidney stone patients were divided by random number table into observation group and control group, with 100 cases in each group. The observation group received flexible ureteroscope lithotripsy, and the control group received percutaneous nephrolithotomy lithotripsy. Comparison were made on perioperative clinical indicators and stone-free rate in two groups, and evaluation were made on safety and clinical treatment effect of the two operative methods. Results The observation group had lower blood urea nitrogen(BUN), creatinine(Cr) in postoperative 1 and 3 d than the control group, and the difference had statistical significance(P〈0.05). The observation group had intraoperative bleeding volume, stone-free rate, hospital stay time, hospitalization fee and postoperative infection rate respectively as(6.17±1.38) ml, 95.00%,(4.15±1.02) d,(3327.40±415.70) yuan and 3.00%, which were all better than(25.33±6.41) ml, 87.00%,(7.36±2.08) d,(4238.00±544.30) yuan, and 10.00% in the control group. Their difference had statistical significance(P〈0.05). Conclusion In clinical application of flexible ureteroscope and percutaneous nephrolithotomy for the treatment of kidney stones, flexible ureteroscope treatment method is better than than that of percutaneous nephrolithotomy treatment in stone-free rate, intraoperative bleeding volume and hospital stay time. So it is worth to be widely applied in clinic.
作者 程世权 刘晖 邓永洪 董宁 邓东成 CHENG Shi-quan LIU Hui DENG Yong-hong et al(Guangdong Province Guangning County People's Hospital, Zhaoqing 526300, Chin)
出处 《中国实用医药》 2017年第6期6-9,共4页 China Practical Medicine
基金 肇庆市科技创新计划项目医疗卫生外科(项目编号:00188971150608032)
关键词 输尿管软镜 经皮肾镜 肾结石 安全性 疗效 Flexible ureteroscope Percutaneous nephrolithotomy Kidney stone Security Curative effect
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