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核素心肌灌注显像对稳定型心绞痛的定位及诊断分析 被引量:6

The analysis of localization and diagnosing of radionuclide myocardial perfusion imaging for stable angina pectoris
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摘要 目的:分析SPECT核素心肌灌注显像对稳定型心绞痛的定位及诊断在临床中的应用价值。方法:选择70例拟诊为稳定型心绞痛(SAP)的患者,对所有患者均行三磷酸腺苷(ATP)负荷-静息99Tcm-甲氧基异丁基异腈(^(99)Tc^m-MIBI)心肌灌注显像(MPI)和冠状动脉造影术(CAG),比较MPI显像对SAP定位及诊断的准确率。结果:在70例患者的两种方法检查中:1MPI检查阳性者共50例;2CAG诊断为SAP者51例;MPI诊断SAP的阳性预测值为92.0%,灵敏度为90.2%,阴性预测值为75.0%,特异度为78.9%;MPI与CAG结论一致的患者共45例,总符合率为90.0%;3CAG检查阳性者共51例,阳性率为72.9%;450例MPI阳性患者中经CAG诊断为SAP共46例,阳性率为92.0%,两种方法检查差异具有统计学意义(x^2=5.72,P<0.05)。结论:^(99)Tc^m-MIBI心肌灌注显像检查在稳定型心绞痛的定位及诊断中具有较高应用价值,能够为临床治疗提供可靠依据。 Objective: To analyze the application value of radionuclide myocardial perfusion imaging in the localization and diagnosis for stable angina pectoris in clinical practice. Methods: A total of 70 patients who had been diagnosed with stable angina pectoris(SAP) were enrolled, and all patients underwent ATP-loaded ATP-99Tcm-MIBI(99Tcm-MIBI) myocardial perfusion imaging(MPI) and coronary angiography(CAG) were used to compare the accuracy of MPI imaging in localization and diagnosis for SAP. Results: In the 70 cases of patients with two methods of examination: 1In MPI diagnosis, positive patients were 50 cases, and the positive predictive value of SAP, sensitivity, negative predictive value and specificity were, respectively, 92.0%, 90.2%, 75.0% and 78.9%. There were 45 patients were consistently diagnosed as SAP by the two methods and the total compliance rate was 90.0%. 2in 70 patients, 51 cases were diagnosed as SAP by CAG examination, the positive rate was 72.9%; 3in 50 MPI positive patients, 46 patients were consistent with the results of CAG diagnosis, and the positive rate was 92.0%. The difference between the two methods was statistically significant(x2= 5.72, P〈0.05). Conclusion: 99Tcm-MIBI myocardial perfusion imaging can be used as a "gatekeeper" in patients with stable angina pectoris, and has high application value in the location and diagnosis for stable angina pectoris. The diagnosis and treatment links of stable angina pectoris can save costs and provide a reliable evidencet for clinical practice.
出处 《中国医学装备》 2017年第4期73-76,共4页 China Medical Equipment
关键词 核素心肌灌注显像 稳定型心绞痛 冠状动脉造影 99Tcm-甲氧基异丁基异腈 诊断 SPECT Radionuclide myocardial perfusion imaging Stable angina pectoris Coronary angiography 99Tcm methoxy isobutyl isonitrile diagnosis SPECT
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