摘要
目的探究临床上通过彩色多普勒超声(B超)技术检测低分子肝素联合免疫球蛋白治疗绒毛膜下血肿(SCH)的疗效以及妊娠结局。方法选择112例早孕期出现SCH的患者为研究对象,随机分为两组,各56例。对照组采取对症安胎治疗,而研究组在对照组的治疗基础上进行低分子肝素联合免疫球蛋白治疗。对所有患者治疗前后均利用B超进行影像学检查,并对临床效果和妊娠结局进行诊断和比较,同时记录治疗和随访期间不良事件的发生情况。结果超声检查发现:研究组治疗总有效率(87.50%)明显高于对照组(64.29%);研究组继续妊娠率(85.71%)远高于对照组(58.93%);研究组不良事件发生率(23.21%)明显低于对照组(51.79%);上述差异均具有统计学意义(P<0.05)。结论临床上利用低分子肝素联合免疫球蛋白治疗绒毛膜下血肿具有显著的疗效,且可利用B超技术在治疗过程中对患者的临床疗效以及妊娠结局起到及时、明确的临床指导作用,为临床治疗方案的正确选择与实施提供明确的影像学依据,值得临床应用推广。
Objective To explore the clinical efficacy and the outcome of pregnancy of low - molecular - weight heparin combined with im-munoglobulin in the treatment of choriocarcinoma （SCH） by color Doppler ultrasonography （B - ultrasonography）. Methods A total of 112 of cases early onset of SCH patients treated in our hospital were selected. The control group were given symptomatic treatment, and based on the treatment of the control group, the study group were given low molecular weight heparin combined with immunoglobulin for treatment. All patients were treated with B - ultrasound before and after treatment, and clinical outcomes and pregnancy outcomes were diagnosed and compared, and the incidence of ad-verse events during treatment and follow - up was recorded. Results Ultrasound examination found The total effective rate of the study group was 87.50% , which was significantly higher than that in the control group 64. 29%. The continued pregnancy rate of the study group was 85. 71% , which was significantly higher than that of the control group 58.93% . The adverse events rate of in the study group was 23. 21% , which was signifi-cantly higher than that in the control group 51.79% , the difference was statistically significant （ P 〈 0 .05 ） . Conclusion Clinical use of low mo-lecular weight heparin combined with immunoglobulin treatment of choriocarcinoma （SCH） has a significant effect, and B - ultrasound performed in the course of treatment of patients with clinical efficacy and pregnancy outcome can play a timely and clear clinical guidance, provide a clear basis for imaging for the correct selection and implementation of clinical treatment programs, worthy of clinical application and promotion.
出处
《临床和实验医学杂志》
2017年第8期803-806,共4页
Journal of Clinical and Experimental Medicine
基金
东莞市科技局立项项目(编号:2016105101073)
关键词
彩色多普勒超声显像
低分子肝素
免疫球蛋白
绒毛膜下血肿
疗效
妊娠结局
Color Doppler ultrasonography
Low molecular weight heparin
Immimoglobulin
Chorionic hematoma
Efficacy
Pregnancy outcome
