摘要
目的:观察针灸联合早期康复对急性脑梗死患者神经功能恢复、脑血流动力学以及血清可溶性E-选择素(SES)、高敏C反应蛋白(hs-CRP)的影响。方法:选取46例急性脑梗死患者,分为康复组(n=23)和对照组(n=23),两组均给予常规药物治疗,对照组给予常规护理措施,康复组在此护理基础上再进行针灸和早期康复。比较两组患者NIHSS评分、Brrthal指数(BI)评分及Fugl-Meyer运动功能评分(FMA);分别检测治疗前、治疗后4周患者脑血流动力学及血清SES、hs-CRP指标。结果:治疗4周后,两组NIHSS评分较治疗前明显降低(P<0.01或0.05),且治疗后康复组NIHSS评分明显更低于对照组(均P<0.05);两组BI及FMA评分均较治疗前明显提高(P<0.01或0.05),且康复组评分明显更高于对照组(均P<0.05)。治疗4周后,两组颈动脉参数Qm、Vm较治疗前明显增高(P<0.01或0.05),Rv、DR明显下降(P<0.01或0.05)。康复组治疗后Qm、Vm较对照组增高明显(均P<0.05),Rv、DR较对照组下降明显(均P<0.05)。治疗4周后,两组血清SES、hs-CRP水平均较治疗前明显降低(P<0.01或0.05),且治疗后康复组血清SES、hs-CRP水平明显更低于对照组(P<0.01或0.05)。结论:针灸联合早期康复能有效改善急性脑梗死患者脑血流动力学,降低血清SES、hs-CRP水平,促进神经功能恢复,提高患者的生活质量。
Objective： To investigate the effect of acupuncture and early rehabilitation training on neurologic function recovery,brain haemodynamics,serum levels of soluble E-selectin（ SES） and high sensitive C-reactive protein（ hs-CRP） in patients with acute cerebral infartion（ ACI）. Methods： 46 patients with acute cerebral infarction were randomly divided into a rehabilitation group（ n = 23） and a control group（ n = 23）. Both groups were treated with routine medication. Control group received conventional nursing measures,while on the basis of the therapy in control group,rehabilitation group received acupuncture and early rehabilitation intervention. NIHSS score,Barthel index score and FMA score were compared between two groups. Brain haemodynamics,SES and hs-CRP were detected before treatment and after treatment of four weeks in both groups. Results： After treatment of four weeks,NIHSS scores in two groups were lower than those pretreatment（ P〈0. 01 or 0. 05）,and the NIHSS score was significantly lower in rehabilitation group than that in control group. BI and FMA scores in both groups were significantly higher than those pretreatment（ P〈0. 01 or 0. 05）,and those in rehabilitation group were significantly higher than those in control group（ all P〈0. 05）. After treatment of four weeks,cerebral haemodynamic parameters Qm,Vm in both groups were significantly higher than those pretreatment（ P〈0. 01 or 0. 05）; Qm and Vm in rehabilitation groups were significantly higher than those in control group（ all P〈0. 05）. Rv,DR in both groups were significantly lower than those pretreatment（ P〈0. 01 or0. 05）,and Rv,DR in rehabilitation group were significantly lower than those in control group（ all P〈0. 05）.After treatment of four weeks,serum SES and hs-CRP levels in both groups were lower than those pretreatment（ P〈0. 01 or 0. 05）. serum SES and hs-CRP levels in rehabilitation group were significantly lower than those in control group（ P〈0. 01 or 0. 05）.
出处
《针灸临床杂志》
2017年第3期12-15,共4页
Journal of Clinical Acupuncture and Moxibustion
关键词
急性脑梗死
针灸
早期康复
可溶性E-选择素
高敏C反应蛋白
Acute cerebral infarction
Acupuncture
Early rehabilitation
Soluble E-selectin
High sensitive C-reactive protein
