摘要
目的:观察适形调强联合参麦注射液治疗局部非小细胞肺癌的临床疗效。方法:选择2013年9月至2015年8月在我院接受治疗的非小细胞肺癌患者86例,随机分为对照组和治疗组,每组各43例,对照组患者接受单纯适形调强放射治疗,治疗组在对照组基础上同时接受参麦注射液治疗,观察2组患者的近期治疗效果,比较2组治疗前后KPS评分的变化及放疗后不良反应的发生情况。结果:治疗组总有效率为81.4%,观察组为76.7%,治疗组高于对照组,但差异无统计学意义(χ2=0.281,P>0.05)。治疗组治疗后KPS评分改善者更多,差异有统计学意义(χ2=6.789,P<0.05)。治疗组各个不良反应的例数均低于对照组,且乏力、放射性食管炎、放射性皮炎、白细胞下降例数显著低于对照组,差异有统计学意义(P<0.05)。结论:适形调强放疗联合参麦注射液治疗非小细胞肺癌的效果优于单纯放疗。
Objective：To observe the clinical curative effect of intensity modulated radiation therapy combined Shenmai injection in treating local non-small cell lung cancer.Methods：Selected 86 cases of non-small cell lung cancer（NSCLC）patients who treated in our hospital from September 2013 to August 2015.Divided patients in control group and treatment group,43 cases each group.Control group accepted simple intensity modulated radiation therapy,and treatment group accepted Shenmai injection treatment on the basis of control group.Observe the recent therapeutic effect of two groups.Compare KPS score and adverse reaction of two groups.Results：The total effective rate of treatment group was 81.4%,control group was 76.7%.Treatment group was higher than control group,but the difference had no statistical significance（χ^2 =0.281,P 〉0.05）.After treatment,the KPS score improved cases of treatment group were more than control group,the difference had statistical significance（χ^2 =6.789,P 〈0.05） .The adverse reaction cases of treatment group were less than control group.Weak,radiation esophagitis,radiodermatitis and leucopenia cases of treatment group were obviously inferior to control group,the difference had statistical significance （P 〈0.05 ） .Conclusion：The curative effect of intensity modulated radiation therapy combined Shenmai injection was better than simple radiotherapy in treating NSCLC.
出处
《世界中医药》
CAS
2016年第12期2722-2724,2728,共4页
World Chinese Medicine
基金
国家自然科学基金项目(编号:30472260)--柞蚕雄蛾有效成分逆转非小细胞肺癌放疗后免疫抑制机理研究
关键词
非小细胞肺癌
放疗
参麦注射液
Non-small cell lung cancer
Radiotherapy
Shenmai injection
