摘要
目的分析2型糖尿病合并脑桥梗死的危险因素。方法收集2008年9月~2009年4月入住浙江大学医学院附属第二医院神经内科的急性脑桥梗死患者共84例,依据是否患有2型糖尿病,将患者分为2型糖尿病合并脑桥梗死组(n=45)和非糖尿病合并脑桥梗死组(n=39),观察收缩压(SBP)、舒张压(DBP)、纤维蛋白原、血浆D-二聚体、糖化血红蛋白(HbAlc)、血浆空腹血糖(FBG)、血浆餐后2 h血糖(PBG)、血尿酸(BUA)、血清甘油三酯(TG)、血清总胆固醇(TC)、血清高密度脂蛋白胆固醇(HDL-C)、血清低密度脂蛋白胆固醇(LDL-C)、血同型半胱氨酸(HCY)、超敏C反应蛋白(CRP),分析两组的危险因素,并分析相关性。结果2型糖尿病合并脑桥梗死组较非糖尿病合并脑桥梗死组的SBP、血浆D-二聚体、纤维蛋白原、FBG、PBG、HbA1c、TC、LDL-C明显升高(P<0.05)。PBG、HbA1c、吸烟、女性是2型糖尿病发生脑桥梗死的危险因素(OR值分别为1.190、6.564、1.7S5、1.708)。结论 2型糖尿病与脑桥梗死关系密切,女性伴有吸烟者,需即时监测和控制血糖,尤其是PBG、HbAlc。
Objective To analyze the risk factors of type 2 diabetes mellitus complicated with pontine infarction. Methods A total of 84 patients with acute pontine infarction who were admitted to the Department of Neurology of the Second Affiliated Hospital of Zhejiang University School of Medicine from September 2008 to April 2009 were selected. Patients were divided into type 2 diabetes complicated with pontine infarction group（n=45） and non-diabetes complicated with pontine infarction group（n=39） according to whether they had type 2 diabetes mellitus. Systolic blood pressure （SBP）, diastolic blood pressure（DBP）, fibrinogen, plasma D-dimer, glycosylated hemoglobin（HbAlc）, plasma fasting blood glucose（FBG）, 2-hour postprandial blood glucose（PBG）, blood uric acid（BUA）, serum triglyceride（TG）, serum total cholesterol（TC）, serum high-density lipoprotein cholesterol（HDL-C）, serum low density lipoprotein cholesterol（LDL-C）, blood homocysteine（HCY）, and high sensitivity C-reactive protcin（CRP） were observed. The risk factors in the two groups were analyzed and the correlation was analyzed. Results The levels of SBP, plasma D-dimer, fibrinogen, FBG, PBG, HbAle, Tc and LDL-C in type 2 diabetes complicated with pontine infarction group were significantly higher than those in non-diabetes complicated with pontine infarction group（P〈0.05）. PBG, HbAlc, smoking, and female patients were the risk factors for pontinc infarction in type 2 diabetes mellitus（OR=1.190, 6.564, 1.785, 1.708, respectively）. Conclusion Type 2 diabetes is closely related to pontine infarction. Blood sugar needs to be monitored and controlled in female smokers, especially for PBG and HbAlc.
出处
《中国现代医生》
2017年第5期82-85,共4页
China Modern Doctor
基金
科技部"十二.五"国家科技支撑计划课题(2013BAI10B03)
关键词
脑桥梗死
2型糖尿病
危险因素
血糖
Pontine infarction
Type 2 diabetes
Risk factors
Blood sugar
