摘要
目的研究分析≥75岁的急性冠状动脉综合征(acute coronary syndrome,ACS)患者临床特征及介入治疗的预后情况。方法选取2012年1月—2015年5月收治的100例≥75岁ACS患者作为观察组,另选同期100例<75岁ACS患者作为对照组。两组患者均行经皮冠状动脉介入治疗(PCI),回顾性分析比较两组患者的临床特点及介入手术的预后情况。结果观察组患者体重指数低于对照组(P<0.01)。观察组收缩压、空腹血糖和肌酐水平均明显高于对照组(P<0.05)。观察组3支病变、前降支、右冠状动脉和左主干病变明显多于对照组(P<0.05,P<0.01)。随访12个月后观察组总体不良心血管事件发生率明显高于对照组(P<0.05)。结论尽管PCI术治疗高龄ACS患者会产生较多的不良心血管事件,但临床疗效较好,仍可作为治疗高龄ACS的有效手段。
Objective To investigate clinical features and prognostic condition of interventional therapy in patients （age ≥75 years old） with acute coronary syndrome （ACS）. Methods A total of 100 patients （age ≥ 75 years old） with ACS admitted between January 2012 and May 2015 were selected as observation group, and other 100 patients （age 〈 75 years old） were selected as control group at the same period. All the patients were treated with pereutaneous coronary intervention （PCI）. Clinical features and prognostic condition of interventional therapy were retrospectively analyzed in two groups. Results In observation group, value of body mass index was lower （P 〈 0. 01 ） ; levels of systolie blood pressure, fasting blood glucose and creatinine were significantly higher （P 〈 0. 05） ; numbers of equal to 3 branehes lesions, the anterior descending coronary artery and right coronary artery and left main lesions was significantly more than those in control group （ P 〈 0.05, P 〈 0.01 ）. After 12 months of follow-up, total incidence rate of adverse cardio- vascular events in observation group was significantly higher than that in control group （ P 〈 0.05 ）. Conclusion Al- though PCI in treatment of elderly patients with ACS has more adverse cardiovascular events, its curative effect is good, and can be used as an effective method in treatment of elderly ACS patients.
出处
《解放军医药杂志》
CAS
2017年第3期53-56,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
陕西省自然科学基金资助项目(97SM38)
