摘要
前列腺癌经传统的雄激素剥夺治疗后,常转归为去势抵抗性前列腺癌(castration-resistant prostate cancer,CRPC),从而影响患者的生活质量。目前,关于CRPC的治疗是研究热点之一,本文就细胞毒性化疗药物、新型雄激素受体拮抗剂、免疫治疗、骨转移靶点治疗以及新型分子靶向治疗方面,对CRPC的治疗研究进行综述,为临床对患者行个性化治疗提供参考。
Prostate cancer treated with traditional androgen deprivation therapy often resulted in castration-resistant prostate cancer（CRPC）,so the quality of patients＇ life was affected.The treatments of CRPC become one of the hotspots in current researches.In this paper we summarized the studies about the treatment in the cytotoxic chemotherapy drugs,the novel androgen receptor antagonist,immune therapy,bone transfer therapeutic targets and novel molecular targeted therapy,aiming at providing the reference for the clinical individualized treatment for patients.
作者
周世豪
陈国俊
ZHOU Shihao CHEN Guojun(Department of Urology, Qinghai University Affiliated Hospital, Xining, 810000, China)
出处
《临床泌尿外科杂志》
2017年第3期241-244,共4页
Journal of Clinical Urology
关键词
前列腺癌
去势抵抗性前列腺癌
治疗方式
prostate cancer
castration-resistant prostate cancer
treatment
