摘要
目的探讨高压氧辅助治疗稳定期慢性阻塞性肺疾病（COPD）的临床价值。方法将98例稳定期COPD患者分为观察组（50例）和对照组（48例），对照组采用常规方式进行治疗，在此基础上观察组加以高压氧进行辅助治疗。对比治疗前后两组患者的动脉血气指标、肺功能及慢阻肺评分（CAT评分）情况。结果两组治疗前动脉氧分压（PaO2）、动脉二氧化碳分压（PaCO2）、动脉血氧饱和度（SaO2）、pH值、1秒用力呼吸气容积（FEV1）、1秒用力呼吸气容积占预计值百分比（FEV1%）、肺活量（FVC）以及CAT评分比较差异未见统计学意义（P〉0.05）；两组治疗后各项动脉血气指标、肺功能指标均有所改善，但观察组变化幅度明显较大，组间比较差异有统计学意义（P〈0.05）。随着治疗的进行，两组CAT评分均呈逐渐下降的趋势发展，但观察组下降幅度明显大于对照组（P〈0.05）。结论在常规治疗的基础上辅以高压氧治疗，能够显著改善稳定期COPD患者的动脉血气及肺功能水平，气流受限得以解除，其肺通气功能明显提升，值得积极推广。
Objective To investigate the clinical value of hyperbaric oxygen therapy in adjuvant treatment of stable chronic obstructive pulmonary disease. Methods Ninety-eight patients with stable chronic obstructive pulmonary disease （COPD） were divided into observation group （50 cases） and control group （48 cases）. The control group was treated with routine treatment, and based on this, the observation group was treated with hyperbaric oxygen. Before and after treatment, the arterial blood gas indexes, pulmonary function and chronic obstructive pulmonary disease assessment score （CAT score） between the two groups were compared. Results Before treatment, PaO2, SaO2, PaCO2, pH value, FEV1, FEV1% and CAT score in the two groups showed no significant difference （ P 〉 0.05 ） ; after treatment, the arterial blood gas index, index of pulmonary function of the two groups were improved, but the differences in the observation group changed significantly, there were significant differences between the two groups （P 〈 0.05）. After the treatment, the CAT scores of the two groups showed a gradual decline trend, but that in the observation group decreased significantly more than the control group （P 〈 0. 05 ）. Conclusions Hyperbaric oxygen therapy on the basis of conventional treatment, can significantly improve the arterial blood gas and pulmonary function, patients with COPD in stable period the airflow limitation is relieved, the pulmonary ventilation function improve significantly, so it should be actively promoted.
出处
《中国实用医刊》
2017年第5期28-30,共3页
Chinese Journal of Practical Medicine
关键词
高压氧
辅助治疗
稳定期慢性阻塞性肺疾病
Hyperbaric oxygen
Adjuvant therapy
Stable chronic obstructive pulmonary disease
